Structure activity relationship of carotenoid derivatives in activation of the electrophile/antioxidant response element transcription system

K Linnewiel, H Ernst, C Caris-Veyrat, A Ben-Dor… - Free Radical Biology …, 2009 - Elsevier
carotenoids activate the electrophile/antioxidant response element (EpRE/ARE) transcription
system … shown to induce the EpRE/ARE system by disrupting the inhibitory activity of Keap1 …

Carotenoids activate the antioxidant response element transcription system

A Ben-Dor, M Steiner, L Gheber, M Danilenko… - Molecular Cancer …, 2005 - AACR
… role of this transcription system in the induction of phase II enzymes by carotenoids. We found
… their antioxidant activity but may be mediated by hydrophilic derivatives of the carotenoids. …

Carotenoids and transcription

Y Sharoni, M Danilenko, N Dubi, A Ben-Dor… - Archives of Biochemistry …, 2004 - Elsevier
… direct activation of the antioxidant response element by carotenoids. However, preliminary
… that carotenoids or their oxidized derivatives interact with a network of transcription systems

[HTML][HTML] The role of lycopene and its derivatives in the regulation of transcription systems: implications for cancer prevention

Y Sharoni, K Linnewiel-Hermoni, G Zango… - The American journal of …, 2012 - Elsevier
… the antioxidant response element transcription system and the inhibition of the transcriptional
… We hypothesized that carotenoids also activate this transcription system, because several …

Modulation of transcriptional activity by antioxidant carotenoids

Y Sharoni, R Agbaria, H Amir, A Ben-Dor… - Molecular Aspects of …, 2003 - Elsevier
… that carotenoids or their oxidized derivatives interact with a network of transcription factors
that are … found in tomatoes in transactivation of PPAR response element (PPARE). Preliminary …

Carotenoids and apocarotenoids in cellular signaling related to cancer: a review

Y Sharoni, K Linnewiel‐Hermoni… - Molecular nutrition & …, 2012 - Wiley Online Library
… , as well as other transcription systems that have an important … /antioxidant response element
pathway and nuclear factor-κB… NF-κB transcription systems by carotenoid derivatives can in …

Role of gene regulation in the anticancer activity of carotenoids

Y Sharoni, M Danilenko, S Walfisch, H Amir… - Pure and applied …, 2002 - degruyter.com
… that carotenoids and their oxidized derivatives interact with a network of transcription systems
… found in tomatoes in transactivation of the PPAR response element. Preliminary results …

The citrus transcription factor CsMADS6 modulates carotenoid metabolism by directly regulating carotenogenic genes

S Lu, Y Zhang, K Zhu, W Yang, J Ye, L Chai… - Plant …, 2018 - academic.oup.com
carotenoids are discussed. These findings advance our understanding of the complex
transcriptional regulation of carotenoid … It is difficult to detect these derivatives because of their low …

Carotenoid derivatives inhibit nuclear factor kappa B activity in bone and cancer cells by targeting key thiol groups

K Linnewiel-Hermoni, Y Motro, Y Miller, J Levy… - Free Radical Biology …, 2014 - Elsevier
… , NFkB nuclear translocation, binding of the NFkB subunits to the NFkB response element,
and activation of transcription. Similar to the effect of the known inhibitor, curcumin, …

Carotenoid biosynthesis and regulation in plants

R Baranski, CI Cazzonelli - Carotenoids: nutrition, analysis and …, 2016 - Wiley Online Library
… pathway to insure a sufficient supply of carotenoid derivatives for the … responsive element)
cis‐acting DNA motifs, which can bind transcription factors and trigger regulation of carotenoid