… of therapy may be even more pronounced in HIV-2 and dual (HIV-D) infection. Thus, we …
by assessing T cell functions, including HIV specific responses in HIV-1-, HIV-2- and HIV-D-…

… HIV-2-specific CD4 + and CD8 + T cells are more polyfunctional that those specific for HIV-1
and that polyfunctional HIV-2-specific T cells … characterize the functional quality of the HIV-2-…

… in HIV-2 infection compared with HIV-1 infection. We therefore present the idea of using HIV-2
as a model for finding a functional cure against HIV. … of HIV-1 and HIV-2 infected cells. In …

… For example, cellular responses to HIV-2 tend to be more polyfunctional and … T-cells may
be more efficient in HIV-2 infection as thymic function is not only preserved for longer in HIV-2 …

… HIV-infected individuals and elite nonprogressors. We find that the functional profile of
HIV-specific CD8 + T cells … , who consistently maintain highly functional CD8 + T cells. This limited …

… cellular immunological correlates of good prognosis in HIV-2 … study of HIV Gag-specific
T cell function in HIV-1- and HIV-2-… , we show that HIV-specific CD4 + T cells from HIV-2-infected …

… Little is known about the function of these early HIV-specific T cells. EBV-specific … T cells
and are important in maturation of CD8 + T-cell function. All of these actions are impaired by HIV …

… may relate to increase NK functional activity early in infection. This study compares NK cell
frequencies and functional activities between HIV-1- and HIV-2-infected subjects in a cross-…

… responses affect the functional profile of HIV-1-specific CD8 + T cells, we next stimulated
PBMCs of HIV-1 controllers and progressors with pooled Gag peptides in the presence or …

… responses compared to untreated HIV-infected individuals. Our data show that … functionality
of HIV-specific CD4 + and CD8 + T cells, preserving key antiviral properties of these cells. …