DNA methylation and the preservation of cell identity

O Bogdanović, R Lister - Current opinion in genetics & development, 2017 - Elsevier
… Nevertheless, targeted deposition and removal of DNA methylation by DNMTs and TET …
the roles of DNA methylation in the establishment and maintenance of cell identity during …

DNA methylation profiles define stem cell identity and reveal a tight embryonic–extraembryonic lineage boundary

CE Senner, F Krueger, D Oxley, S Andrews… - … cells, 2012 - academic.oup.com
… endoderm (XEN) stem cells contribute predominantly to tissues … cell types is defined by a
unique DNA methylation profile. Despite their distinct developmental origin, TS and XEN cells

[HTML][HTML] Cell-type specific DNA methylation patterns define human breast cellular identity

P Novak, MR Stampfer, JL Munoz-Rodriguez… - PLoS …, 2012 - journals.plos.org
… Tissue specific differential methylation has also been well … of differential DNA methylation
between different cell types derived … and fibroblast cells, promoter region DNA methylation was …

[HTML][HTML] A DNA methylation atlas of normal human cell types

N Loyfer, J Magenheim, A Peretz, G Cann, J Bredno… - Nature, 2023 - nature.com
DNA methylation is a fundamental epigenetic mark that governs gene expression and
chromatin organization, thus providing a window into cellular identity and developmental …

DNA methylation and epigenetic control of cellular differentiation

DA Khavari, GL Sen, JL Rinn - Cell cycle, 2010 - Taylor & Francis
DNA methylation is a classic and powerful example of the epigenetic inheritance of cellular
identity that is widely used in eukaryotes.DNA methylation confers distinct epigenetic states …

[HTML][HTML] Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx

S Dhawan, S Georgia, S Tschen, G Fan, A Bhushan - Developmental cell, 2011 - cell.com
… the methylated region of Arx locus. Our results suggest that propagation of DNA methylation
pattern … structure that can be stably inherited through cell division to preserve β cell identity. …

Relevance of DNA methylation at enhancers for the acquisition of cell identities

E Kreibich, AR Krebs - FEBS letters, 2023 - Wiley Online Library
… globally contribute to the expression of genes defining cell identities. Here, we will review the
… , and how these may contribute to the determination of cell identities during development. …

[HTML][HTML] Tet3 regulates cellular identity and DNA methylation in neural progenitor cells

M Santiago, C Antunes, M Guedes, M Iacovino… - Cellular and Molecular …, 2020 - Springer
… a role in maintaining both cellular identity and DNA methylation levels in neural precursor
… of neural cell identity by maintaining DNA methylation levels in neural precursor cells. …

DNA methylation dynamics in cellular commitment and differentiation

M Suelves, E Carrió, Y Núñez-Álvarez… - Briefings in functional …, 2016 - academic.oup.com
cell identity. The aim of the present review is to discuss the major advances concerning the
DNA methylation dynamics during cellDNA methylation as a modulator of cell identity and …

Transdifferentiation occurs without resetting development-specific DNA methylation, a key determinant of full-function cell identity

A Radwan, J Eccleston, O Sabag, H Marcus… - Proceedings of the …, 2024 - pnas.org
… Recognizing the importance of DNA methylation in establishing cell identity, we developed
a unique approach to analyze specific changes in DNA methylation associated with …