Aneuploidy and DNA methylation as mirrored features of early human embryo development

EN Tolmacheva, SA Vasilyev, IN Lebedev - Genes, 2020 - mdpi.com
… these stages is such that we can only guess what an imbalance of DNA methylation may
contribute to incorrect chromosome segregation at this stage—the hypomethylation of repetitive …

Trans effects of chromosome aneuploidies on DNA methylation patterns in human Down syndrome and mouse models

M Mendioroz, C Do, X Jiang, C Liu, HK Darbary… - Genome biology, 2015 - Springer
… find early maturation of methylation patterns in DS brain and … seq of brain DNA from mouse
models with sub-chromosomal … and shows that multiple chromosome 21 genes contribute to …

Heritable alteration of DNA methylation induced by whole‐chromosome aneuploidy in wheat

L Gao, M Diarso, A Zhang, H Zhang, Y Dong… - New …, 2016 - Wiley Online Library
… alterations in a DNA methylation pattern as a result of whole-chromosome aneuploidy in any
organism. Our analysis of seven types of whole-chromosome aneuploidy encompassing all …

DNA methylation-based sex classifier to predict sex and identify sex chromosome aneuploidy

Y Wang, E Hannon, OA Grant, TJ Gorrie-Stone… - BMC genomics, 2021 - Springer
chromosomes, thousands of CpG sites on autosomes also show very different DNA methylation
patterns … co-variate, when undertaking methylation and phenotype association studies. …

The epigenetic origin of aneuploidy

LA Herrera, D Prada, MA Andonegui… - Current …, 2008 - ingentaconnect.com
… role of DNA methylation in chromosome stability and the impact of modifications on this
epigenetic mark in correct chromosome … Currently, it is well known that aneuploidy is observed in …

DNA methylation profiles of human active and inactive X chromosomes

AJ Sharp, E Stathaki, E Migliavacca… - Genome …, 2011 - genome.cshlp.org
… analysis of DNA methylation patterns on the active and inactive X chromosomes. Consistent
with previous studies, we observe that XCI is accompanied by gains in methylation at the …

DNA methylation patterns of metaphase chromosomes in human preimplantation embryos

AA Pendina, OA Efimova, ID Fedorova… - … and Genome Research, 2010 - karger.com
… Meanwhile, the sequential changes of DNA methylation, specific for chromosomes and their
… stage study of DNA methylation patterns in homologous metaphase chromosomes of triploid …

Evaluation of genome-wide DNA methylation profile of human embryos with different developmental competences

M Yang, X Tao, K Scott, Y Zhan, RT Scott Jr… - Human …, 2021 - academic.oup.com
… between DNA methylation level and ploidy status (aneuploidy [n … the DNA methylation level
on the chromosome scale. … have lower methylation level on the involved chromosome while …

DNA methylation patterns in lung carcinomas

GP Pfeifer, TA Rauch - Seminars in cancer biology, 2009 - Elsevier
… The relative contribution of genetic and epigenetic changes as well as gross chromosomal
aberrations (ie aneuploidy) to the different stages of lung tumorigenesis needs to be …

Sites of differential DNA methylation between placenta and peripheral blood: molecular markers for noninvasive prenatal diagnosis of aneuploidies

EA Papageorgiou, H Fiegler, V Rakyan, S Beck… - The American journal of …, 2009 - Elsevier
… analysis to enable chromosome-wide identification of DNA methylation patterns in a …
methylation patterns of chromosomes 13, 18, 21, X, and Y in female whole blood and placental DNA