Cilofungin (LY121019) shows nonlinear plasma pharmacokinetics and tissue penetration in rabbits
JW Lee, P Kelly, J Lecciones, D Coleman… - Antimicrobial agents …, 1990 - Am Soc Microbiol
… Cilofungin given intravenously by bolus injections of 50 mg/kg of body weight once daily for
… Cilofungin was ineffective, however, in a rabbit model of Candida endocarditis when doses …
… Cilofungin was ineffective, however, in a rabbit model of Candida endocarditis when doses …
Evaluation of cilofungin (LY121019) for treatment of experimental Candida albicans endocarditis in rabbits
A Padula, HF Chambers - Antimicrobial agents and …, 1989 - Am Soc Microbiol
… of cilofungin (LY121019) for aortic valve endocarditis caused by Candida albicans in rabbits
… of experimental candidal endocarditis in rabbits, (ii) to determine whether cilofungin is …
… of experimental candidal endocarditis in rabbits, (ii) to determine whether cilofungin is …
Efficacy of cilofungin therapy administered by continuous intravenous infusion for experimental disseminated candidiasis in rabbits
MS Rouse, BM Tallan, JM Steckelberg… - Antimicrobial agents …, 1992 - Am Soc Microbiol
… the effect of cilofungin diluent on survival of infected rabbits and (ii) compare the efficacy of …
cilofungin (LY121019) for treatment of experimental Candida albicans endocarditis in rabbits. …
cilofungin (LY121019) for treatment of experimental Candida albicans endocarditis in rabbits. …
Comparative efficacies of cilofungin (Ly121019) and amphotericin B against disseminated Candida albicans infection in normal and granulocytopenic mice
N Khardori, H Nguyen, LC Stephens… - Antimicrobial agents …, 1993 - Am Soc Microbiol
… Padula and Chambers (20) reported that cilofungin was not effective in a rabbit model of
candida endocarditis when a dosage of 50mg/kg given intravenously twice daily for 7 days was …
candida endocarditis when a dosage of 50mg/kg given intravenously twice daily for 7 days was …
Experimental antifungal chemotherapy in granulocytopenic animal models of disseminated candidiasis: approaches to understanding investigational antifungal …
TJ Walsh, JW Lee, E Roilides, P Francis… - Clinical infectious …, 1992 - academic.oup.com
… Cilofungin (LY 121019) is a semisynthetic lipopeptide of the echinocandin class of … ]
observed that cilofungin was not effective in a rabbit model of candidal endocarditis when dosages …
observed that cilofungin was not effective in a rabbit model of candidal endocarditis when dosages …
Antifungal effects of the nonlinear pharmacokinetics of cilofungin, a 1, 3-beta-glucan synthetase inhibitor, during continuous and intermittent intravenous infusions in …
TJ Walsh, JW Lee, P Kelly, J Bacher… - Antimicrobial agents …, 1991 - Am Soc Microbiol
… Cilofungin (LY-121019) is a semisynthetic lipopeptide of the echinocandin class of … observed
that cilofungin was not effective in a rabbit model of Candida endocarditis when a dosage …
that cilofungin was not effective in a rabbit model of Candida endocarditis when a dosage …
In vitro activity of the new semi-synthetic polypeptide cilofungin (LY121019) againstAspergillus andCandida species
A Huang, F Edwards, EM Bernard, D Armstrong… - European Journal of …, 1990 - Springer
… animal models, cilofungin appeared to be ineffective in Candida albicans endocarditis (13),
but it was … (L¥121019) for treatment of experimental Candida albicans endocarditis in rabbits. …
but it was … (L¥121019) for treatment of experimental Candida albicans endocarditis in rabbits. …
Current developments in anti-fungal agents
AJ Carrillo-Muñoz, G Quindós… - … -Anti-Infective Agents, 2004 - ingentaconnect.com
… with a related structure to cilofungin (LY-121019, Lilly, USA) [9,25,116,124]. Both the spectrum
of action and the toxicity profile are superior to those of cilofungin, being highly active in …
of action and the toxicity profile are superior to those of cilofungin, being highly active in …
New agents for the treatment of systemic fungal infections–Current status
JH Rex, S Arikan - Expert opinion on emerging drugs, 2002 - Taylor & Francis
… in neutropenic rabbits. Preliminary pharmacokinetic studies in noninfected rabbits showed
… Cilofungin (LY-121019), which was first developed by scientists at Lilly Pharmaceuticals in …
… Cilofungin (LY-121019), which was first developed by scientists at Lilly Pharmaceuticals in …
Comparison of cilofungin and amphotericin B for therapy of murine candidiasis
KR Smith, KM Lank, CG Cobbs, GA Cloud… - Antimicrobial agents …, 1990 - Am Soc Microbiol
… a Candida endocarditis model also observed that cilofungin did … with rabbits, Chapman and
coauthors observed that cilofungin … Cilofungin (LY121019), an antifungal agent with specific …
coauthors observed that cilofungin … Cilofungin (LY121019), an antifungal agent with specific …
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