8072 Background: We performed an individual pts data meta-analysis using trials that
compared G or E vs platinum doublet chemotherapy (CT) on OS outcome. Methods: Treatment-…

… If validated, our results suggest that gefitinib and erlotinib may have a role in the chemoprevention
of CNS metastases from NSCLC. Clin Cancer Res; 18(16); 4406–14. ©2012 AACR. …

… Our study revealed the obvious disparity in drug selection between erlotinib and gefitinib
in clinical practice. Type of TK inhibitors did not influence treatment outcomes in patients with …

… treated with either erlotinib or gefitinib at our institution. The clinical characteristics of the
patients were reviewed, and the efficacy and toxicity of erlotinib and gefitinib were compared for …

… Background: There is increasing interest in the impact of EGFR and KRAS genotype on …
treated with gefitinib or erlotinib. We created a mutation registry to track protocol-based clinical …

… The Mantel–Haenszel fixed effect method8, 9 was used to … We developed a clinical significance
curve and risk-benefit … the additional clinical benefit of afatinib versus gefitinib 5 and the …

… -effects models for gefitinib and erlotinib; insufficient information was available from the afatinib
studies. Depending on the model, gefitinib appears similar to erlotinib … erlotinib. Data for …

… had a radiographic response to erlotinib. All of the … clinical data in their response to both
gefitinib and erlotinib. The second study evaluated 14 unselected patients that had failed gefitinib…

… The analysis of clinical data suggests a difference in the effectiveness of erlotinib and gefitinib…
the different response to gefitinib and erlotinib may depend on the effects of various EGFR …

… The present findings shed light on mechanisms underlying variability in drug exposure
and clinical effects for the EGFR tyrosine kinase inhibitors gefitinib and erlotinib. …