[HTML][HTML] Lung cancer molecular mutations and abnormal glycosylation as biomarkers for early diagnosis

S Yang, J Xia, Z Yang, M Xu, S Li - Cancer Treatment and Research …, 2021 - Elsevier
… and oncogenic regulation of protein glycosylation. Based on to … We hypothesize that
glycoproteins whose glycosylation can … glycosylation in lung cancer cell culture and clinical

Altered cell adhesion and glycosylation promote cancer immune suppression and metastasis

H Läubli, L Borsig - Frontiers in immunology, 2019 - frontiersin.org
… in cell surface glycosylation (3, 4). Cancer-associated glycosylation promotes the interaction
of … context of altered glycosylation as a ubiquitous characteristic of cancer progression with a …

Glycosylation in health and disease

C Reily, TJ Stewart, MB Renfrow, J Novak - Nature Reviews Nephrology, 2019 - nature.com
glycosylation patterns are altered in multiple human diseases, including congenital disorders
of glycosylation (… and chronic inflammatory diseases, and cancer. We also provide specific …

[PDF][PDF] Sweetening the deal: Glycosylation and its clinical applications

Y Zhang, L Sun - J. Biomed. Sci, 2020 - researchgate.net
… depth of research into glycosylation has brought on newer … dived into various clinical aspects
involving glycosylation, with … in the study of the clinical aspects of glycosylation and will be …

Aberrant glycosylation as immune therapeutic targets for solid tumors

Y Matsumoto, T Ju - Cancers, 2023 - mdpi.com
… in clinical Phase I study for the patients with Tn + MUC1 positive advanced cancers (…
The other related CART therapies-targeting MUC1 are also being tested in clinical trials (discussed …

Clinical application of quantitative glycomics

W Peng, J Zhao, X Dong, A Banazadeh… - Expert review of …, 2018 - Taylor & Francis
Introduction: Aberrant glycosylation has been associated with many diseases. Decades of
research activities have reported many reliable glycan biomarkers of different diseases which …

The role of O-glycosylation in human disease

A Magalhães, HO Duarte, CA Reis - Molecular Aspects of Medicine, 2021 - Elsevier
… layers of regulation of the cellular glycosylation machinery, being organ-, … glycosylation.
Particular relevance is given to genetic disorders of glycosylation, infectious diseases and cancer

Aberrant N-glycosylation in cancer: MGAT5 and β1,6-GlcNAc branched N-glycans as critical regulators of tumor development and progression

M de-Souza-Ferreira, ÉE Ferreira… - Cellular Oncology, 2023 - Springer
… possible future clinical implications, such … glycosylation profiles for improving clinical diagnosis
or prognosis, (2) the development of vaccines or drugs targeting a glycan or glycosylation

Cancer stem cell marker glycosylation: nature, function and significance

BW Mallard, J Tiralongo - Glycoconjugate Journal, 2017 - Springer
… into the pathological processes involved in cancer progression including metastasis, tumour
… that glycosylation is altered in most cancers, with alterations in glycosylation occurring at the …

Glycosylation alterations in lung and brain cancer

H Lemjabbar-Alaoui, A McKinney, YW Yang… - Advances in cancer …, 2015 - Elsevier
… We then use specific examples to highlight the diverse roles of glycosylation in these two …
in cancer. We suggest that alterations in glycosylation in lung and brain cancer provide novel …