… ability to critically appraise the quality of clinical practice guidelines has been a barrier to their
… clinical practice guidelines that make recommendations related to the use of drug therapy …

… in clinical geriatric practice, where patients often have several medical conditions and are
taking more than one drug. Clinical trials of conditions commonly affecting older people often …

Randomized clinical trials have shown that antihypertensive treatment reduces the risk of
heart failure (HF). Limited evidence exists, however, on whether and to what extent this benefit …

Background The objective of the Scandinavian Society of Anaesthesiology and Intensive
Care Medicine ( SSAI ) task force on fluid and drug therapy in adults with acute respiratory …

… are important in clinical practice and whether it is necessary to compensate for these
betweenassay differences by adjusting the target therapeutic ranges used for cyclosporine TDM-in …

… In practice, we must stop speaking of and thinking of clinical pharmacy as a specialty. Our
minimum goal should be for every pharmaceutical practice to be a clinical practice, … practice …

… drug has been approved for marketing, and after many years of therapeutic use in clinical
practice… The application of safety PGx in clinical practice is intended to avoid significant, drug-…

… therapy — particularly with respect to dosage — still have to be developed. Moreover, to apply
PGx efficiently in clinical drug development, and later in drug therapy… fields of drug therapy …

… The therapeutic index of the drug will also influence test utility. After considering all of these
… It is not surprising that few drugs satisfy these requirements. Drugs (and enzymes) for which …

… test in 2004, it has hardly been used to screen drug conversion or metabolic pathways in
research or clinical practice. The field of pharmacogenomics seems to have stagnated with few …