Tyrosine Kinase Inhibitor Activity in Patients with NSCLC Harboring Uncommon EGFR Mutations: A Retrospective International Cohort Study (UpSwinG)
… This study further illustrates that uncommon EGFR mutations are highly heterogeneous and
compound mutations are common in patients with EGFR mutation-positive NSCLC. However…
compound mutations are common in patients with EGFR mutation-positive NSCLC. However…
[HTML][HTML] Uncommon EGFR mutations in a cohort of Chinese NSCLC patients and outcomes of first-line EGFR-TKIs and platinum-based chemotherapy
J Shi, H Yang, T Jiang, X Li, C Zhao… - … of Cancer Research, 2017 - ncbi.nlm.nih.gov
… Therefore, more large-scale cohort studies and data in this field should be welcomed to …
with uncommon EGFR mutations in this study is relatively high compared with other studies, …
with uncommon EGFR mutations in this study is relatively high compared with other studies, …
Afatinib treatment in a large real‐world cohort of nonsmall cell lung cancer patients with common and uncommon epidermal growth factor receptor mutation
CH Huang, JS Ju, TH Chiu, ACC Huang… - … Journal of Cancer, 2022 - Wiley Online Library
… light on new treatment options for patients of EGFR exon 20 insertion mutation. In our study,
patients of the type-II uncommon EGFR mutation exhibited a bipolar tumour behaviour, with …
patients of the type-II uncommon EGFR mutation exhibited a bipolar tumour behaviour, with …
A Nationwide Study on the Impact of Routine Testing for EGFR Mutations in Advanced NSCLC Reveals Distinct Survival Patterns Based on EGFR Mutation …
B Koopman, BN Cajiao Garcia, CCHJ Kuijpers… - Cancers, 2021 - mdpi.com
… of treatment options for the current uncommon EGFR mutations. Our results indicate that
the … In smaller cohorts, EGFR mutation status and response rates have been reported, but …
the … In smaller cohorts, EGFR mutation status and response rates have been reported, but …
[HTML][HTML] Uncommon EGFR mutations in non-small-cell lung cancer: A systematic literature review of prevalence and clinical outcomes
T John, A Taylor, H Wang, C Eichinger, C Freeman… - Cancer …, 2022 - Elsevier
… Given the low patient numbers in uncommon EGFR mutation cohorts in individual studies,
it is valuable to examine the breadth of evidence across studies; consequently, our SLR was …
it is valuable to examine the breadth of evidence across studies; consequently, our SLR was …
Outcomes of first-generation EGFR-TKIs against non-small-cell lung cancer harboring uncommon EGFR mutations: a post hoc analysis of the BE-POSITIVE study
S Pilotto, A Rossi, T Vavalà, A Follador, M Tiseo… - Clinical Lung Cancer, 2018 - Elsevier
… The specific types of uncommon EGFR mutations detected in this analysis are described
in Table 2. The most frequent EGFR mutations were G719X and L861Q, detected in 6 (17.2%) …
in Table 2. The most frequent EGFR mutations were G719X and L861Q, detected in 6 (17.2%) …
Non-classic EGFR mutations in a cohort of Dutch EGFR-mutated NSCLC patients and outcomes following EGFR-TKI treatment
JL Kuiper, SMS Hashemi, E Thunnissen… - British journal of …, 2016 - nature.com
… Multiple uncommon EGFR mutations or an uncommon EGFR … a cohort of Dutch (ie,
predominant Caucasian) EGFR-mutated NSCLC patients retrospectively. The purpose of this study …
predominant Caucasian) EGFR-mutated NSCLC patients retrospectively. The purpose of this study …
Efficacy and safety of dacomitinib in treatment-naïve patients with advanced NSCLC harboring uncommon EGFR mutation: an ambispective cohort study
X Pu, Y Zhou, Y Kong, B Chen, A Yang, J Li, K Li, Y Xu… - Bmc Cancer, 2023 - Springer
… uncommon EGFR mutations in a real-world setting. Therefore, in this study, we conducted
a real-world, ambispective cohort study … NSCLC patients with uncommon EGFR mutations. …
a real-world, ambispective cohort study … NSCLC patients with uncommon EGFR mutations. …
Uncommon EGFR mutations in advanced non-small cell lung cancer
… uncommon EGFR mutations and summarizes reported outcomes when treated with EGFR-TKIs.
… However, as stated previously, the S768I EGFR mutation cohort contained 8 patients in …
… However, as stated previously, the S768I EGFR mutation cohort contained 8 patients in …
… Resistance Mechanisms in Patients with Non-Small Cell Lung Cancer Carrying Uncommon EGFR Mutations: A Comparative Cohort Study in China (AFANDA Study)
HS Li, SZ Wang, HY Xu, X Yan, JY Zhang, SY Lei, T Li… - Cancers, 2022 - mdpi.com
… This was a comparative cohort study in two … uncommon EGFR mutations treated with afatinib
or dacomitinib were eligible for evaluation. Two cohorts were employed in the current study. …
or dacomitinib were eligible for evaluation. Two cohorts were employed in the current study. …
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