Randomized, double-blind controlled phase 3 trial comparing the immunogenicity of high-dose and standard-dose influenza vaccine in adults 65 years of age and …

AR Falsey, JJ Treanor, N Tornieporth… - The Journal of …, 2009 - academic.oup.com
… HA per 0.5-mL dose from the following influenza strains: A/New … The control product was
licensed trivalent influenza vaccine (… μg of HA per 0.5-mL dose from the same 3 influenza strains …

Efficacy of high-dose versus standard-dose influenza vaccine in older adults

CA DiazGranados, AJ Dunning… - … England Journal of …, 2014 - Mass Medical Soc
… We conducted a phase IIIb–IV, multicenter, randomized, double-blind, active-controlled
trial … hemagglutinin per strain) with standard-dose trivalent, inactivated influenza vaccine (IIV3-SD …

[HTML][HTML] Immunogenicity and safety of Fluzone® intradermal and high-dose influenza vaccines in older adults≥ 65 years of age: A randomized, controlled, phase II …

P Tsang, GJ Gorse, CB Strout, M Sperling… - Vaccine, 2014 - Elsevier
… , controlled, multicenter, phase II study to evaluate the immunogenicity and safety of an
investigational intradermal (ID) trivalent influenza vaccine (TIV) and a high-dose (… with ID vaccine

High-dose trivalent influenza vaccine compared to standard dose vaccine in elderly adults: safety, immunogenicity and relative efficacy during the 2009–2010 season

CA DiazGranados, AJ Dunning, E Jordanov, V Landolfi… - Vaccine, 2013 - Elsevier
phase IIIb, multicenter, randomized, double-blind, controlled trial was conducted to compare
High-Dose (HD) trivalent inactivated influenza vaccine … ) to standard dose (SD) vaccine (15 …

Time to change dosing of inactivated quadrivalent influenza vaccine in young children: evidence from a phase III, randomized, controlled trial

VK Jain, JB Domachowske, L Wang… - Journal of the …, 2017 - academic.oup.com
… to establish lot-to-lot consistency of influenza vaccines. In this analysis, the double-dose IIV4
did not reach superiority to the standard-dose in the overall population, the older age group …

Immunogenicity, large scale safety and lot consistency of an intradermal influenza vaccine in adults aged 18–60 years: Randomized, controlled, phase III trial

R Arnou, P Eavis, JR De Juanes Pardo… - … vaccines, 2010 - Taylor & Francis
influenza vaccination, and vaccination coverage in this age-range remains low.A series of
population-based studies of influenza vaccination … in recent years, vaccine uptake remains …

[HTML][HTML] … of the new intradermal influenza vaccine compared to the standard subcutaneous vaccine in subjects 65 years and older: A randomized controlled phase III …

R Arakane, R Annaka, A Takahama, K Ishida… - Vaccine, 2015 - Elsevier
… at high risk for influenza, the immunogenicity … influenza vaccine with the novel intradermal
(ID) injection system. In the previous exploratory phase I/II study of the ID vaccine with a dose

Efficacy, immunogenicity, and safety of an oral influenza vaccine: a placebo-controlled and active-controlled phase 2 human challenge study

D Liebowitz, K Gottlieb, NS Kolhatkar… - The Lancet Infectious …, 2020 - thelancet.com
… efficacy of influenza vaccines. In 2015, we did a phase 1 trial of an oral influenza vaccine,
VXA… the vaccine to the current phase 2 trial. The aim of this study was to evaluate efficacy of the …

Synthetic Influenza vaccine (FLU-v) stimulates cell mediated immunity in a double-blind, randomised, placebo-controlled Phase I trial

O Pleguezuelos, S Robinson, GA Stoloff… - Vaccine, 2012 - Elsevier
… Despite their global use these vaccines must … for Influenza vaccines addressing these issues
and here we report the results of a Phase Ib trial of a novel synthetic Influenza vaccine (FLU-…

[HTML][HTML] … , tolerability, and immunogenicity of influenza vaccination with a high-density microarray patch: Results from a randomized, controlled phase I clinical trial

AH Forster, K Witham, ACI Depelsenaire… - PLoS …, 2020 - journals.plos.org
… Our results suggest that influenza vaccine delivered by HD-MAP was safe and well tolerated,
with evidence to suggest that dose-sparing and enhanced immune responses are induced …