Resolving crystal polymorphisms by finding “stationary points” from quantitative analysis of crystal growth response surfaces

LF Kuyper, CW Carter Jr - Journal of crystal growth, 1996 - Elsevier
… We have previously suggested that response surface experiments are an appropriate
technique for the quantitative analysis necessary to realize this goal [18]. In this work, we have …

Review of the Application of Raman Spectroscopy in Qualitative and Quantitative Analysis of Drug Polymorphism

Z Sun, B Lin, X Yang, B Zhao, H Zhang… - Current Topics in …, 2023 - ingentaconnect.com
… for detecting polymorphic form of drug tablets, and more researchers have used TRS for
quantitative analysis of drug crystals. Aina [99] used TRS for the first time to detect polymorphic

Comparison of polymorphic molecular crystal structures through Hirshfeld surface analysis

JJ McKinnon, FPA Fabbiani… - Crystal growth & …, 2007 - ACS Publications
… structure imply that a Hirshfeld surfaces energy-matching process would be likely to depend
on a quantitative, as well as qualitative, analysis, which is beyond the scope of this work but …

Quantitative analysis of mannitol polymorphs. X-ray powder diffractometry—exploring preferred orientation effects

SNC Roberts, AC Williams, IM Grimsey… - … and biomedical analysis, 2002 - Elsevier
… , warrants quantitative control to ensure that the polymorphic … on the accuracy of quantitative
analysis using XRPD. From this… of XRPD for quantitative analysis depending on the crystal

Using terahertz pulsed spectroscopy to quantify pharmaceutical polymorphism and crystallinity

CJ Strachan, PF Taday, DA Newnham… - Journal of …, 2005 - Elsevier
… were analyzed using TPS and levels of polymorphism and … crystalline indomethacin, and
thermotropic liquid crystalline … In this article, quantitative analyses of the solid-state forms of …

Polymorphism and solvatomorphism 2010

HG Brittain - Journal of pharmaceutical sciences, 2012 - Elsevier
… Papers and patents that deal with polymorphism (crystal systems for which a substance can
… in a quantitative analysis method for the hemihydrate, amorphous, and three polymorphic

Conformational polymorphism in organic crystals

A Nangia - Accounts of chemical research, 2008 - ACS Publications
… molecule occur in different crystal forms, the phenomenon is termed conformational
polymorphism. Occasionally, more than one conformer is present in the same crystal structure. The …

Quantitative analysis of polymorphic mixes of zirconia by X‐ray diffraction

HK Schmid - Journal of the American Ceramic Society, 1987 - Wiley Online Library
Nonlinear calibration curves of weight fraction vs integrated intensity ratio arc obtained for
polymorphic mixtures of ZrO 2 by means of powder X‐ray diffraction. The (C + M) and (T + M) …

Conformational polymorphism. The influence of crystal structure on molecular conformation

J Bernstein, AT Hagler - Journal of the American Chemical …, 1978 - ACS Publications
… of conformational polymorphism, in which a molecule adopts significantly different conformations
in different crystal polymorphs, is elucidated. A combination of quantitative analysis of …

The computational prediction of pharmaceutical crystal structures and polymorphism

SL Price - Advanced drug delivery reviews, 2004 - Elsevier
… However, although such a computational prediction scheme is not yet available, there is
considerable academic work aimed at a quantitative understanding of polymorphism that is …