Cytokines and atherosclerosis: a comprehensive review of studies in mice

R Kleemann, S Zadelaar, T Kooistra - Cardiovascular research, 2008 - academic.oup.com
… of these cytokines in atherogenesis. … mouse atherosclerosis studies investigating the role
of the interleukins IL-1,-2,-4,-5,-6,-10,-12,-18, and -20, the macrophage-associated cytokines

Inflammatory cytokines in atherosclerosis: current therapeutic approaches

D Tousoulis, E Oikonomou, EK Economou… - European heart …, 2016 - academic.oup.com
… The actions of pro-atherogenic cytokines can be better appreciated based on experimental
studies with hyperlipidaemic mouse models. For example, TNF-α −/− , apolipoprotein E (ApoE…

Cytokines and immune responses in murine atherosclerosis

PJH Kusters, E Lutgens - Methods in Mouse Atherosclerosis, 2015 - Springer
… In this review, we aim to give a structural overview of the cytokines involved in
atherosclerosis (Table 1), with special focus on the interleukin family and mouse studies. …

Recent advances on the role of cytokines in atherosclerosis

H Ait-Oufella, S Taleb, Z Mallat… - … , thrombosis, and vascular …, 2011 - Am Heart Assoc
… -α plays a key role in atherosclerosis was obtained in experimental studies using TNF-deficient
apolipoprotein E (apoE) −/− mice showing that atherosclerotic lesion size in the aortic …

Cytokines in atherosclerosis: pathogenic and regulatory pathways

A Tedgui, Z Mallat - Physiological reviews, 2006 - journals.physiology.org
… of atherosclerosis. Based on our current knowledge of the role of cytokines in atherosclerosis
the beginning of the 1990s when mouse models of atherosclerosis, apolipoprotein E (apoE)…

Reduced atherosclerosis and inflammatory cytokines in apolipoprotein-E-deficient mice lacking bone marrow-derived interleukin-1α

Y Kamari, A Shaish, S Shemesh, E Vax… - Biochemical and …, 2011 - Elsevier
studied these mice when fed a normal chow diet containing 4.5% fat by weight (0.02%
cholesterol) in two time points namely, at the age of 16 weeks, representing early atherosclerotic

[HTML][HTML] Cytokines in atherosclerosis: Key players in all stages of disease and promising therapeutic targets

DP Ramji, TS Davies - Cytokine & growth factor reviews, 2015 - Elsevier
atherosclerosis have been analyzed in mouse model systems, and the outcomes are
summarized in Table 1, Table 2. It should be noted that different studiesatherosclerosis in mouse

Cytokines: roles in atherosclerosis disease progression and potential therapeutic targets

JWE Moss, DP Ramji - Future medicinal chemistry, 2016 - Taylor & Francis
… of atherosclerotic mouse models have greatly improved our understanding of the role of
cytokines and … Normally wild-type mice do not develop atherosclerosis, however, ApoE knockout …

Metoprolol Reduces Proinflammatory Cytokines and Atherosclerosis in ApoE−/− Mice

MA Ulleryd, E Bernberg, LJ Yang… - BioMed research …, 2014 - Wiley Online Library
… reduce progression of atherosclerosis in ApoE −/− mice and therefore studied whether long-…
We also studied the potential effects of metoprolol on proinflammatory cytokines known to …

Both gut microbiota and cytokines act to atherosclerosis in ApoE−/− mice

Q Liu, Y Li, X Song, J Wang, Z He, J Zhu, H Chen… - Microbial …, 2020 - Elsevier
… the microbiota and cytokines changed together in the process of mice with atherosclerosis.
… mechanisms involved in the process of atherosclerosis. These results imply the dysbiosis …