Treatment of symptomatic congenital cytomegalovirus infection with valganciclovir

CFM Jansen, MC Toet, CMA Rademaker… - Journal of perinatal …, 2005 - degruyter.com
Valganciclovir (VGCV) is a prodrug of GCV with improved … treatment to oral GCV w7x for
treatment of neonates. We present a neonate with congenital CMV infection, who was treated

Valganciclovir for symptomatic congenital cytomegalovirus disease

DW Kimberlin, PM Jester, PJ Sánchez… - … England Journal of …, 2015 - Mass Medical Soc
… one third of patients as part of the natural history of this disease, prospective, controlled
trial designs are critical to assess treatment benefit in patients with congenital CMV infections. …

Treatment of symptomatic congenital cytomegalovirus infection with intravenous ganciclovir followed by long-term oral valganciclovir

J Amir, DG Wolf, I Levy - European journal of pediatrics, 2010 - Springer
… The main side effect of treatment was transient neutropenia. In conclusion, prolonged …
congenital CMV infection with intravenous ganciclovir followed by oral valganciclovir is safe, and it …

Intrauterine therapy of cytomegalovirus infection with valganciclovir: review of the literature

V Seidel, C Feiterna-Sperling, JP Siedentopf… - Medical microbiology …, 2017 - Springer
… asymptomatic CMV infection and consecutive fetal CMV infection confirmed by high CMV
VL in AF. Serologic findings in the first trimester hinted at a primary CMV infection. The first …

Pharmacokinetic and pharmacodynamic assessment of oral valganciclovir in the treatment of symptomatic congenital cytomegalovirus disease

DW Kimberlin, EP Acosta, PJ Sánchez… - … Journal of infectious …, 2008 - academic.oup.com
CMV infection (40,000 infants/year) [6]. Of … valganciclovir after administration of intravenous
ganciclovir in version 2.0 of the study, 15 study subjects restarted valganciclovir treatment at …

Valganciclovir: a review of its use in the management of CMV infection and disease in immunocompromised patients

RS Cvetkovic, K Wellington - Drugs, 2005 - Springer
… , valganciclovir appears to have some advantages over ganciclovir. Therefore, when used as
prophylaxis against CMV infection … of CMV retinitis in patients with AIDS, oral valganciclovir

[HTML][HTML] Prophylactic versus preemptive oral valganciclovir for the management of cytomegalovirus infection in adult renal transplant recipients

JA Khoury, GA Storch, DL Bohl, RM Schuessler… - American Journal of …, 2006 - Elsevier
… of CMV infection and disease were used (23). Asymptomatic CMV infection was defined
as the detection of CMV … Episodes of CMV DNAemia separated by at least two consecutive …

Antiviral treatment of cytomegalovirus infection

A Ahmed - … Targets (Formerly Current Drug Targets-Infectious …, 2011 - ingentaconnect.com
… Since then, three additional systemic antiviral agents have been approved for use in the
US: valganciclovir (VGCV), the oral prodrug of GCV, foscarnet (FOS), and cidofovir (CDV) (Table …

Cytomegalovirus ulcer: successful treatment with valganciclovir

EM Lambert, J Strasswimmer, R Lazova… - Archives of …, 2004 - jamanetwork.com
valganciclovir is absorbed vs 6% to 9% of oral ganciclovir. Plasma levels of oral valganciclovir
… the first report of successful treatment of cutaneous CMV infection with an oral medication. …

Clinical pharmacokinetics and pharmacodynamics of ganciclovir and valganciclovir in children with cytomegalovirus infection

C Stockmann, JK Roberts, ED Knackstedt… - Expert Opinion on …, 2015 - Taylor & Francis
… the effectiveness of ganciclovir and valganciclovir in preventing CMV disease in a …
valganciclovir-treated patients developed CMV infection as opposed to 2/20 (10%) …