Expression of various genes is controlled by DNA methylation during mammalian development
M Ehrlich - Journal of cellular biochemistry, 2003 - Wiley Online Library
… developmental genes [… genes during development by differential DNA methylation. There
are several caveats in studies of whether DNA methylation is a regulator of tissue-specific gene …
are several caveats in studies of whether DNA methylation is a regulator of tissue-specific gene …
DNA methylation
R Singal, GD Ginder - Blood, The Journal of the American …, 1999 - ashpublications.org
… plays a critical role in silencing specific genes during development and cell differentiation.
The intrinsic mutagenicity of 5-mC, activation of proto-oncogenes through hypomethylation, …
The intrinsic mutagenicity of 5-mC, activation of proto-oncogenes through hypomethylation, …
DNA methylation in early development
TM Geiman, K Muegge - … Reproduction and Development …, 2010 - Wiley Online Library
… developmental genes such as the Hox and Pax family members show preferential DNA
methylation… Though developmental changes in DNA methylation are crucial, we are only starting …
methylation… Though developmental changes in DNA methylation are crucial, we are only starting …
DNA methylation in early development
A Razin, R Shemer - Human Molecular Genetics, 1995 - academic.oup.com
… strongly suggest that DNA methylation is involved in embryo development. Perhaps the most
… methylation changes have been observed during the early steps of embryo development. …
… methylation changes have been observed during the early steps of embryo development. …
DNA methylation: roles in mammalian development
ZD Smith, A Meissner - Nature Reviews Genetics, 2013 - nature.com
… two developmental periods, primordial germ cell (PGC) specification and the early embryo,
in which DNA methylation … principles of DNA methylation in mammalian development and set …
in which DNA methylation … principles of DNA methylation in mammalian development and set …
DZNep is a global histone methylation inhibitor that reactivates developmental genes not silenced by DNA methylation
… We then looked at the effects of DZNep on DNA methylation. Pyrosequencing showed that
the treatment of MCF7 cells with 5 μmol/L DZNep did not affect the levels of DNA methylation …
the treatment of MCF7 cells with 5 μmol/L DZNep did not affect the levels of DNA methylation …
Notes on the role of dynamic DNA methylation in mammalian development
TH Bestor, JR Edwards… - Proceedings of the …, 2015 - National Acad Sciences
… and represses genes via reversible DNA methylation. … DNA methylation does have essential
roles in irreversible promoter silencing, as in the monoallelic expression of imprinted genes…
roles in irreversible promoter silencing, as in the monoallelic expression of imprinted genes…
DNA methylation in animal development
RR Meehan - Seminars in cell & developmental biology, 2003 - Elsevier
… of methylation at distinct residues of the N-terminal tails of histone H3 and H4. This review
describes the role of the DNA methylation-… remodelling activities) in animal development. …
describes the role of the DNA methylation-… remodelling activities) in animal development. …
Dynamics and function of DNA methylation in plants
… DNA methylation are crucial for development. In both plants and mammals, DNA methylation
is catalysed by conserved DNA … donor, whereas active DNA demethylation involves a base …
is catalysed by conserved DNA … donor, whereas active DNA demethylation involves a base …
DNA methylation patterns and epigenetic memory
A Bird - Genes & development, 2002 - genesdev.cshlp.org
… The heritability of methylation states and the secondary nature of the … methylation support
the idea that DNA methylation is adapted for a specific cellular memory function in development…
the idea that DNA methylation is adapted for a specific cellular memory function in development…
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- dna methylation in plants
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- dna methylation and demethylation
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- regulation of gene transcription dna methylation
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