Drug release characteristics of PAMAM dendrimer–drug conjugates with different linkers

YE Kurtoglu, MK Mishra, S Kannan… - International journal of …, 2010 - Elsevier
… -bonded conjugates of 4th generation PAMAM dendrimers in various media are reported.
The … PAMAM dendrimer–ibuprofen conjugates without linkers were found to be stable against …

PAMAM dendrimers as efficient drug and gene delivery nanosystems for cancer therapy

F Abedi-Gaballu, G Dehghan, M Ghaffari, R Yekta… - Applied materials …, 2018 - Elsevier
… to PAMAM-G3 and G5 dendrimers via acid-labile ester linkers. … the linker was an ester type,
the UA release from FA-PAMAM-… of the PAMAM dendrimer has been carried out for different

Design considerations for PAMAM dendrimer therapeutics

SN Goonewardena, JD Kratz, H Zong, AM Desai… - Bioorganic & medicinal …, 2013 - Elsevier
… Additionally, we demonstrate that the linker-modified MTX compounds had similar … In
agreement with our other findings, only cells treated with the dendrimer–eMTX (2 and 3) showed …

DNA microarrays with PAMAM dendritic linker systems

R Benters, CM Niemeyer, D Drutschmann… - Nucleic acids …, 2002 - academic.oup.com
… surface 7 against repeated regeneration procedures, microarrays containing two different
generation of a novel linker system comprising PAMAM dendrimers covalently attached to …

PEGylated PAMAM dendrimers: Enhancing efficacy and mitigating toxicity for effective anticancer drug and gene delivery

D Luong, P Kesharwani, R Deshmukh, MCIM Amin… - Acta biomaterialia, 2016 - Elsevier
… and influence of PEGylation on various biopharmaceutical properties of PAMAM dendrimers.
… Using PEG as a linker can avoid the steric hindrance cause by the folding of drugs into the …

PAMAM dendrimers: destined for success or doomed to fail? Plain and modified PAMAM dendrimers in the context of biomedical applications

M Labieniec-Watala, C Watala - Journal of pharmaceutical sciences, 2015 - Elsevier
dendrimers as drug delivery systems dominated all other fields… of the using of PAMAM
dendrimers in various areas of science … either directly (via peptide bond) or with the use of a linker. …

Preparation and evaluation of PAMAM dendrimer-based polymer gels physically cross-linked by hydrogen bonding

H Cong, L Zhou, Q Meng, Y Zhang, B Yu, Y Shen… - Biomaterials …, 2019 - pubs.rsc.org
dendrimers have been used as versatile linkers in some projects. In this work, polymer gels
composed of PAMAM dendrimersDendrimers with different amino/ester ratios on the surface …

Interactions between PAMAM dendrimers and bovine serum albumin

B Klajnert, L Stanisławska, M Bryszewska… - Biochimica et Biophysica …, 2003 - Elsevier
PAMAM dendrimers are based on an ethylenediamine core and … We used three types of
PAMAM dendrimers with different surface … An attractive approach is to use dendrimers as linker

In vitro evaluation of third generation PAMAM dendrimer conjugates

M Najlah, S Freeman, M Khoder, D Attwood… - Molecules, 2017 - mdpi.com
… engineering of dendrimers for different applications such as … as a linker/spacer between the
drug and dendrimer resulted … and G3 PAMAM dendrimers, via a diethylene glycol linker. The …

A review on structural aspects and applications of PAMAM dendrimers in analytical chemistry: Frontiers from separation sciences to chemical sensor technologies

I Hussain, N Muhammad, Q Subhani, D Shou… - TrAC Trends in …, 2022 - Elsevier
… and easy fabrication to different substrates. In this paper, significant knowledge of PAMAM
dendrimers is reviewed from the perspective of different structural parts, particularly the …