… This nonsignificant 5% reduction in the risk of pneumonia (rate ratio [RR… risk reduction
associated with ICS withdrawal in COPD. In this article, we assess the effect of ICS discontinuation …

… We sought to estimate the risk of asthma exacerbation in patients who stop low-dose inhaled
corticosteroids (ICSs) compared with those who continue ICSs in randomized controlled …

… The aim of this double-blind single center study (the COPE study) was to investigate the
effect of discontinuation of the inhaled corticosteroid fluticasone propionate (FP) on …

… the risk of asthma exacerbation in stable asthmatics who reduce inhaled corticosteroids (ICS…
of asthma exacerbation is likely lower than that for discontinuing ICS altogether. In addition, …

… reductions: SGRQ score change of 4 points and FEV 1 change of 100 mL. The thresholds
for clinically important relative risk reductions … important absolute risk reductions were based …

… withdrawal of inhaled corticosteroid (ICS) in chronic obstructive pulmonary disease (COPD).
We performed a quantitative synthesis in order to assess real impact of ICS discontinuation …

… withdrawal of inhaled glucocorticoids, the risk of exacerbation would be similar to that with
continued use of inhaled glucocorticoids … conducted the Withdrawal of Inhaled Steroids during …

… Effect of discontinuation of inhaled corticosteroids in patients with chronic obstructive
pulmonary disease: the COPE study. Am J Respir Crit Care Med. 2002;166:1358–1363. …

… ), it appears safe to consider stopping inhaled corticosteroids. Potential advantages will be
to reduce the drug burden on patients, reduce adverse effects, and make financial savings. …

… We report the first randomised placebo-controlled study of withdrawal of long-term inhaled
corticosteroids in patients with COPD recruited in primary care. Risk of COPD exacerbation …