… diseases. Several strategies are used to generate such disease models using either embryonic
stem cells (ES cells) or … for the establishment of models and their use in drug screening. …

… iPSC-based disease models using organoids will integrate into these approaches to drug
discovery by improving preclinical drug screening, design and validation using highly disease-…

… disease modelling so far has focused on Mendelian disorders of high clinical penetrance and
with a recognized cellular … disease entities can be modelled with iPSCs remains uncertain. …

… disease, haematopoietic recovery after co-transplantation of MSCs along with haematopoietic
stem cells … Finally, we review the emerging area based on the use of MSCs as a target cell …

… Here, we provide an overview of the use of human stem cells to model diseases. First, we
discuss the use of adult stem cells and disease models based on pluripotent stem cells (PSCs)…

… about disease modelling using pluripotent stem cells, as … stem cell derived progeny are
functionally mature in order to provide accurate information about the diseases being modelled. …

… (hiPSCs) has opened new perspectives for modelling and … of disease-specific pluripotent
stem cells in disease modelling and … of disease-specific human pluripotent stem cells for drug …

… animal model for sporadic AD, we propose in this review that induced pluripotent stem cells,
… a promising novel tool for disease modelling and drug discovery for the sporadic form of AD. …

… proficient stem cell-disease models and on establishing an effective therapeutic treatment.
In this review, we discuss important breakthroughs of stem cell-based models highlighting …

… stem cell (hPSC) technologies has shifted from cell therapy to in vitro disease modelling and
drug … Details are provided for all disease-specific human induced pluripotent stem cell lines …