The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

TH Rushmore, MR Morton, CB Pickett - Journal of Biological Chemistry, 1991 - Elsevier
… region contained a responsive element, the antioxidant responsive element (ARE), … sequence,
which has been named the electrophile responsive element, contains the core sequence

Antioxidant response element

AK Jaiswal - Biochemical pharmacology, 1994 - Elsevier
… genes in response to 12-O-tetradecanoylphorbol-13-acetate … elements are imperfect APl
binding consensus sequences. … DNA consensus sequence electrophile-responsive element. …

Functional antioxidant responsive elements

WW Wasserman, WE Fahl - Proceedings of the National …, 1997 - National Acad Sciences
… an internal standard, and pUC-19 carrier DNA by calcium phosphate coprecipitation with a
2-… are identified by screening the GenBank database with our consensus sequence, and (iv) …

… of a variant antioxidant response element in the promoter of the human glutamate-cysteine ligase modifier subunit gene: revision of the ARE consensus sequence

AM Erickson, Z Nevarea, JJ Gipp… - Journal of Biological …, 2002 - ASBMB
… The ARE consensus sequence of the −312 construct was mutated from ATGACTCAGCA to
AgGACTCAGCA using the 5′–3′ MORPH DNA site-directed mutagenesis kit to create the −…

Integrating iron and oxygen/antioxidant signals via a combinatorial array of DNA–(antioxidant response elements) and mRNA (iron responsive elements) sequences

EC Theil - Journal of inorganic biochemistry, 2006 - Elsevier
… via DNA (ARE-antioxidant response element) and mRNA (IRE-iron responsive element) …
proteins/aconitase homologues), than the DNA-ARE and protein repressors, eg, Bach1. Iron …

[HTML][HTML] Antioxidant response elements: Discovery, classes, regulation and potential applications

A Raghunath, K Sundarraj, R Nagarajan, F Arfuso… - Redox biology, 2018 - Elsevier
… , it was termed an electrophile-responsive element (EpRE). A DNA motif with an inverse repeat
5'-… The consensus sequence of the TRE is defined as TGA(C/G)TCA. The ARE contains a …

Molecular basis for the contribution of the antioxidant responsive element to cancer chemoprevention

JD Hayes, M McMahon - Cancer letters, 2001 - Elsevier
… C A-3′ DNA recognition motif for AP-1. Although the ARE consensus sequence is clearly
distinct from the classic AP-1 binding site, it is nevertheless related to the DNA-binding sites of …

The antioxidant/electrophile response element motif

DE Nerland - Drug metabolism reviews, 2007 - Taylor & Francis
… to a DNA recognition sequence known as antioxidant response element (ARE) or electrophile
response element (… of the DNA consensus sequence required for functional activity. J. Biol. …

Identification of polymorphic antioxidant response elements in the human genome

X Wang, DJ Tomso, BN Chorley, HY Cho… - Human molecular …, 2007 - academic.oup.com
… binding to DNA elements and a consensus sequence for binding … consensus sequence
5′-TMAnnRTGAYnnnGCRwwww-3′w-3′ (where W = A or T; M = A or C, ‘core’ consensus

… induction of heme oxygenase-1 and chemoprotective phase 2 enzymes by electrophiles and antioxidants: regulation by upstream antioxidant-responsive elements  …

T Prestera, P Talalay, J Alam, YI Ahn, PJ Lee… - Molecular …, 1995 - Springer
… Although these elements are “AP-1-like” in their sequences (AP-1 is a family of … activator
DNA-binding proteins that bind to the TPA-responsive element [TRE] consensus sequence [TGA …