DNA methylation and chromatin modification
HH Ng, B Adrian - Current opinion in genetics & development, 1999 - Elsevier
… for an inhibitor of DNA methylation, 5-aza-dC, to derepress silent rRNA genes. This study
provides an early indication for a link between DNA methylation and histone deacetylation. …
provides an early indication for a link between DNA methylation and histone deacetylation. …
DNA methylation and chromatin–unraveling the tangled web
KD Robertson - Oncogene, 2002 - nature.com
… between DNA methylation and chromatin … chromatin states may dictate genome-wide DNA
methylation patterning. The mammalian DNA methylation machinery – properties of the DNA …
methylation patterning. The mammalian DNA methylation machinery – properties of the DNA …
Epigenetics: interaction of DNA methylation and chromatin
M Nakao - Gene, 2001 - Elsevier
… DNA methyltransferases, methyl-CpG binding proteins, histone-modifying enzymes, chromatin
… basis for transcription, DNA replication, mutation and repair, DNA recombination, and …
… basis for transcription, DNA replication, mutation and repair, DNA recombination, and …
DNA methylation and chromatin structure
J Lewis, A Bird - FEBS letters, 1991 - Wiley Online Library
… chromatin structure, DNA methylation also represses transcription. A protein (MeCP) which
binds specifically to methylated DNA … of DNA methylation on both chromatin and transcription. …
binds specifically to methylated DNA … of DNA methylation on both chromatin and transcription. …
DNA methylation, chromatin inheritance, and cancer
… Understanding the molecular determinants of both normal and abnormal patterns of chromatin
formation and DNA methylation thus holds great promise for our understanding of cancer …
formation and DNA methylation thus holds great promise for our understanding of cancer …
Epigenetics, DNA methylation, and chromatin modifying drugs
M Szyf - Annual review of pharmacology and toxicology, 2009 - annualreviews.org
… , demethylation is targeted to genes by chromatin modification changes. Transcription
factors … In summary, DNA methylation pattern and chromatin structure are found in a dynamic …
factors … In summary, DNA methylation pattern and chromatin structure are found in a dynamic …
The role of DNA methylation in setting up chromatin structure during development
… To test whether DNA methylation actually has a role in the assembly of chromatin during
normal … programmed to be either methylated or unmethylated in all cell types of the mouse 2 . …
normal … programmed to be either methylated or unmethylated in all cell types of the mouse 2 . …
Cancer as an epigenetic disease: DNA methylation and chromatin alterations in human tumours
M Esteller, JG Herman - The Journal of Pathology: A Journal of …, 2002 - Wiley Online Library
… methylation of CpG islands in one X-chromosome in women, which renders these genes
inactive. Finally, although DNA methylation … aim, sometimes DNA methylation accomplishes this …
inactive. Finally, although DNA methylation … aim, sometimes DNA methylation accomplishes this …
DNA Methylation-Related Chromatin Remodeling in Activity-Dependent Bdnf Gene Regulation
… We propose a model in which DNA methylation and its related chromatin remodeling play
critical roles in regulating gene transcription in response to neuronal activity (Fig. 4D). CpG …
critical roles in regulating gene transcription in response to neuronal activity (Fig. 4D). CpG …
DNA methylation and chromatin structure: the puzzling CpG islands
P Caiafa, M Zampieri - Journal of cellular biochemistry, 2005 - Wiley Online Library
… Histone modifications, DNA methylation, and proteins able to bind methylated DNA play a
dynamic role in determining chromatin structure suitable for gene expression or silencing. At …
dynamic role in determining chromatin structure suitable for gene expression or silencing. At …
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