… Differential methylation effects on sperm DNA have been demonstrated to be toxin-specific
[… otherwise, will likely manifest in specific human disease conditions or kinetics. However, the …

… models to assess DNA methylation in disease is an area of investigation that is still in its
early stages, but is showing considerable promise for providing insights into human disease. A …

… will examine recent evidence for AP in human disease. … Cogent criteria were designed to
identify AP in human disease. The … candidates for AP in human disease were identified. Alleles …

… Our current view of DNA methylation mechanism and its functional meaning is rapidly …
de novo and maintenance DNA methylation, the general association of DNA methylation with …

… , alters the structure of the DNA molecule resulting in possible modifications of … DNA
methylation through its transcriptional consequences may have an important role in human disease…

… ATRX, a chromatin-remodeling factor, is another DNA methylation modifier which leads
to human disease if mutated. Mutations in this gene occur in alpha-thalassemia/ mental …

… Another class of human disease linked to DNA methylation is the large group of pathologies
associated with repeat instability. Fragile X syndrome (FRAXA) is one such disease which …

… the beginner with the knowledge of DNA methylation process and its role in age … to DNA
methylation technique is provided in Section 2. Section 3 reviews the role of DNA methylation in …

… Changes in human DNA methylation patterns are an important feature of cancer development
… to be shown to cause any known human disease via insertional mutagenesis. Expression …

… via DNA methylation has … of DNA methylation, evaluate its effects on gene expression
and discuss related key enzymes. In addition, we summarize recent aberrant DNA methylation …