Genomic imprinting and human disease
R Hirasawa, R Feil - Essays in biochemistry, 2010 - portlandpress.com
… In the mouse, establishment of DNA methylation imprints in the developing male germ
cells initiates at E (embryonic day) 14.5–15.5. Paternal ICRs become fully methylated several …
cells initiates at E (embryonic day) 14.5–15.5. Paternal ICRs become fully methylated several …
Sex-specific DNA methylation: impact on human health and development
… , particularly in DNA methylation, will … development and neurodegeneration. From a medicine
and health standpoint, sex-specific methylation studies have shed light on human disease …
and health standpoint, sex-specific methylation studies have shed light on human disease …
DNA methylation profiling in human Huntington's disease brain
RAG De Souza, SA Islam, LM McEwen… - Human molecular …, 2016 - academic.oup.com
… -associated DNA methylation alterations at queried sites, we found that DNA methylation
may … Moreover, our data suggest that DNA methylation may, in part, contribute to tissue-specific …
may … Moreover, our data suggest that DNA methylation may, in part, contribute to tissue-specific …
Chromosome territory reorganization in a human disease with altered DNA methylation
MR Matarazzo, S Boyle… - Proceedings of the …, 2007 - National Acad Sciences
… , such as DNA methylation, and higher-… DNA methylation at particular sites, including CpG
islands on the inactive X chromosome (Xi). This allows the specific effects of DNA methylation …
islands on the inactive X chromosome (Xi). This allows the specific effects of DNA methylation …
DNA methylation contributes to natural human variation
… DNA methylation and transcriptional regulation. Therefore, we integrated DNA methylation
… decreased gene expression associated to promoter hypermethylation in 12.9% (13 out of 101…
… decreased gene expression associated to promoter hypermethylation in 12.9% (13 out of 101…
[PDF][PDF] Epigenetic changes in health and disease: DNA Methylation in human development, infection and non-communicable diseases
PAJ Perera - Ceylon J. Sci, 2018 - pdfs.semanticscholar.org
… to be the outcome of aberration in genomic DNA methylation. These epigenome changes
being … Earlier human disease was thought to originate from changes in the base sequence of …
being … Earlier human disease was thought to originate from changes in the base sequence of …
Alterations in cardiac DNA methylation in human dilated cardiomyopathy
… Epigenetic mechanisms are increasingly recognized as causes and modulators of human
disease. Therefore, we studied genome‐wide cardiac DNA methylation in DCM patients and …
disease. Therefore, we studied genome‐wide cardiac DNA methylation in DCM patients and …
Fetal programming: link between early nutrition, DNA methylation, and complex diseases
A Chmurzynska - Nutrition reviews, 2010 - academic.oup.com
… in DNA methylation and histone modifications. Dicer 1 deficiency in mice leads to decreased
DNA methylation, and these methylation … DNA methylation. PiRNAs are essential for the …
DNA methylation, and these methylation … DNA methylation. PiRNAs are essential for the …
[HTML][HTML] Genetic impacts on DNA methylation: research findings and future perspectives
S Villicaña, JT Bell - Genome biology, 2021 - Springer
… potential insights for human disease onset and progression. In this review, we summarize
recent milestones in characterizing the human genetic basis of DNA methylation variation over …
recent milestones in characterizing the human genetic basis of DNA methylation variation over …
De novo DNMTs and DNA methylation: novel insights into disease pathogenesis and therapy from epigenomics
S Leppert, MR Matarazzo - Current pharmaceutical design, 2014 - ingentaconnect.com
… Chromosome territory reorganization in a human disease with altered DNA methylation.
Proc Natl Acad Sci USA 2007; 104: 16546-51. [46] Hansen RS, Wijmenga C, Luo P, et al. …
Proc Natl Acad Sci USA 2007; 104: 16546-51. [46] Hansen RS, Wijmenga C, Luo P, et al. …