Epigenetic small molecule modulators of histone and DNA methylation

AT Hauser, D Robaa, M Jung - Current Opinion in Chemical Biology, 2018 - Elsevier
… on small molecule modulators of DNA and histone methylation. … DNA methylation, histone
modifications and noncoding RNAs [4]. DNA methylation is deposited and maintained by DNA-…

[HTML][HTML] Epigenetic modulation of DNA methylation by nutrition and its mechanisms in animals

N Zhang - Animal nutrition, 2015 - Elsevier
DNA methylation process contributed the most significance of the … modulation of DNA
methylation were reviewed here. … DNA methylation; second, provision of cofactors modulating the …

[HTML][HTML] DNA methylation: Precise modulation of chromatin structure and dynamics

S Li, Y Peng, AR Panchenko - Current opinion in structural biology, 2022 - Elsevier
DNA methylation is also involved in the modulation of three-dimensional chromatin structure
[46]. Indeed, the DNA methylation loss resulting from mutations in DNA-… DNA methylation

[HTML][HTML] Role of DNA methylation in modulating transcription factor occupancy

MT Maurano, H Wang, S John, A Shafer, T Canfield… - Cell reports, 2015 - cell.com
… abrogation of DNA methylation. The small fraction of sites that show methylation-dependent …
Our results suggest that DNA methylation is not a primary groundskeeper of genomic TF …

Biological and biochemical modulation of DNA methylation

R Lo, R Weksberg - Epigenomics, 2014 - Taylor & Francis
… This review will focus on DNA methylation and DNA methyltransferases with … modulating
DNA methylation. Other physiological and biochemical factors that can modify DNA methylation

Modulation of DNA methylation by a sesquiterpene lactone parthenolide

Z Liu, S Liu, Z Xie, RE Pavlovicz, J Wu, P Chen… - … of Pharmacology and …, 2009 - ASPET
Modulation of DNA methylation with DNA methylation … Currently, effective DNA methylation
inhibitors are mainly limited … In this article, we report that parthenolide 1) inhibits DNA

Dietary fat and obesity as modulators of breast cancer risk: Focus on DNA methylation

MG Donovan, SN Wren, M Cenker… - British Journal of …, 2020 - Wiley Online Library
… review is to highlight studies documenting modulating effects of dietary fatty acids (… DNA
CpG methylation. We focus our review on DNA methylation given that detecting CpG methylation

Targeting DNA methylation

JPJ Issa, HM Kantarjian - Clinical Cancer Research, 2009 - AACR
… of DNA methylation. As soon as embryogenesis begins, a massive decrease in DNA methylation
… and gene mutation confirmed that epigenetic modulation precedes clonal elimination in …

[HTML][HTML] Phytochemicals in cancer prevention: modulating epigenetic alterations of DNA methylation

S Pop, AM Enciu, I Tarcomnicu, E Gille… - Phytochemistry Reviews, 2019 - Springer
… EGCG exerts its epigenetic modulator capacity of DNA methylation processes indirectly, by
acting as a substrate for COMT catalyzed methylation reaction (Bistulfi et al. 2010) or directly …

[HTML][HTML] An epigenomic roadmap to induced pluripotency reveals DNA methylation as a reprogramming modulator

DS Lee, JY Shin, PD Tonge, MC Puri, S Lee… - Nature …, 2014 - nature.com
… We find that DNA methylation gain during … low methylation and strong engagement of
histone marks, whereas genes with CpG-poor promoters are safeguarded by methylation. Such …