Development of in vivo drug-induced neurotoxicity models
HS Sharma, P Menon, JV Lafuente… - … opinion on drug …, 2014 - Taylor & Francis
… -induced neurotoxicity in vivo models for suitable therapeutic strategies to induce …
Areas covered: In this review, psychostimulants drugs-induced neurotoxicity is discussed in …
Areas covered: In this review, psychostimulants drugs-induced neurotoxicity is discussed in …
Clinical detection and assessment of drug induced neurotoxicity
CA Naranjo, L Fornazzari, EM Sellers - Progress in Neuro …, 1981 - Elsevier
1. Drug-induced neurological disease is a relatively common problem. For example, the
Boston Collaborative Drug Surveillance Program reported that in 11,526 hospitalized patients, …
Boston Collaborative Drug Surveillance Program reported that in 11,526 hospitalized patients, …
Drug-induced neurotoxicity in addiction medicine: From prevention to harm reduction
… provide a link between these drug-induced brain changes and … of neurotoxicity consequent
to commonly abused drugs (… of drug-induced neurotoxic damage to clinical practice. …
to commonly abused drugs (… of drug-induced neurotoxic damage to clinical practice. …
Machine learning modeling and insights into the structural characteristics of drug-induced neurotoxicity
X Zhao, Y Sun, R Zhang, Z Chen, Y Hua… - Journal of Chemical …, 2022 - ACS Publications
… neurotoxic chemicals. In this study, we focused on the computational modeling for drug-induced
neurotoxicity … the structural characteristics of neurotoxic chemicals. Based on the clinical …
neurotoxicity … the structural characteristics of neurotoxic chemicals. Based on the clinical …
Anti-cancer drug induced neurotoxicity and identification of Rho pathway signaling modulators as potential neuroprotectants
SE James, H Burden, R Burgess, Y Xie, T Yang… - Neurotoxicology, 2008 - Elsevier
… We found that all of these anti-cancer drugs induce substantial neurotoxicity evidenced by
… Therefore, the neurotoxicity resulting from exposure to the anti-cancer drugs cisplatin and …
… Therefore, the neurotoxicity resulting from exposure to the anti-cancer drugs cisplatin and …
The relevance of anesthetic drug–induced neurotoxicity
TG Hansen, T Engelhardt, M Weiss - JAMA pediatrics, 2017 - jamanetwork.com
… drugs in early life. There is no welldefined and specific longterm phenotype associated with
exposure to anesthetic drugs. … to antiepileptic drugs. 3 An a priori expectation that anesthetic …
exposure to anesthetic drugs. … to antiepileptic drugs. 3 An a priori expectation that anesthetic …
[HTML][HTML] Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models
… In this project we aimed to develop a novel in vitro approach for more comprehensive
drug-induced neurotoxicity testing by providing insight into mechanisms of neurotoxicity. Since the …
drug-induced neurotoxicity testing by providing insight into mechanisms of neurotoxicity. Since the …
Cancer-treatment-induced neurotoxicity—focus on newer treatments
JB Stone, LM DeAngelis - Nature reviews Clinical oncology, 2016 - nature.com
… A variety of drugs can induce specific cranial neuropathies; the causes are either idiosyncratic
or part of a more-diffuse peripheral neuropathy resulting from treatment with a drug such …
or part of a more-diffuse peripheral neuropathy resulting from treatment with a drug such …
[HTML][HTML] Mechanisms of chemotherapy-induced neurotoxicity
… Many widely used chemotherapy drugs including platinum-… may cause direct and indirect
neurotoxicity. In this review we … -induced neurotoxicity is crucial for the development of drugs …
neurotoxicity. In this review we … -induced neurotoxicity is crucial for the development of drugs …
Fluorouracil-induced neurotoxicity
NA Pirzada, II Ali, RM Dafer - Annals of Pharmacotherapy, 2000 - journals.sagepub.com
… delayed neurotoxicity. Acute neurotoxicity manifests as encephalopathy or as cerebellar
syndrome; seizures, as seen in our patient, have rarely been reported. Acute neurotoxicity due …
syndrome; seizures, as seen in our patient, have rarely been reported. Acute neurotoxicity due …