Polyethylene glycol–polyamidoamine dendritic micelle as solubility enhancer and the effect of the length of polyethylene glycol arms on the solubility of pyrene in …
H Yang, JJ Morris, ST Lopina - Journal of colloid and interface science, 2004 - Elsevier
… According to our results, PEG arm length has a significant affect on pyrene water solubility.
Short PEG arms (eg, PEG 750) do not have much interaction between each other [26], thus …
Short PEG arms (eg, PEG 750) do not have much interaction between each other [26], thus …
[HTML][HTML] Preparation of pluronic/bile salt/phospholipid mixed micelles as drug solubility enhancer and study the effect of the PPO block size on the solubility of pyrene
L Wang, M Peng, Y Zhu, S Tong, X Cao… - Iranian Journal of …, 2014 - ncbi.nlm.nih.gov
… In this study, we have demonstrated that PPO chain length affect the thermodynamic properties
of Pluronic/BS/PS-MM micellization which, in turn, affect their solubilization potential for …
of Pluronic/BS/PS-MM micellization which, in turn, affect their solubilization potential for …
Influence of the introduction of a solubility enhancer on the formulation of lipidic nanoparticles with improved drug loading rates
A Malzert-Fréon, G Saint-Lorant, D Hennequin… - European Journal of …, 2010 - Elsevier
… The very interesting antineoplastic effect of these compounds belonging to the tripentone …
= 30–45%), no obvious impact of the length of the chain of fatty acids on the solubility of the …
= 30–45%), no obvious impact of the length of the chain of fatty acids on the solubility of the …
Chemical enhancer solubility in human stratum corneum lipids and enhancer mechanism of action on stratum corneum lipid domain
SA Ibrahim, SK Li - International journal of pharmaceutics, 2010 - Elsevier
… is thought to be independent of its chemical structure (ie, polar head group or alkyl chain
length… studied (except UD), and suggests that the permeation enhancing effect of the enhancers …
length… studied (except UD), and suggests that the permeation enhancing effect of the enhancers …
Solubility enhancers for oral drug delivery: can chemical structure manipulation be avoided?
CK Kim, JS Park - American Journal of Drug Delivery, 2004 - Springer
… therapeutic effects of poorly water-soluble drugs mainly by improving the poor solubility. …
formation may not eliminate the solubility problems of all poorly water-soluble drugs. Moreover, …
formation may not eliminate the solubility problems of all poorly water-soluble drugs. Moreover, …
An investigation on the effect of drug physicochemical properties on the enhancement strength of enhancer: The role of drug-skin-enhancer interactions
W Xu, C Liu, Y Zhang, P Quan, D Yang… - International Journal of …, 2021 - Elsevier
… Furthermore, drug-specific molecular mechanisms of POCC enhancement effect were
explored using solubility parameters calculation, FT-IR, molecular docking, ATR-FTIR, Raman …
explored using solubility parameters calculation, FT-IR, molecular docking, ATR-FTIR, Raman …
Effects of chemical enhancers on human epidermal membrane: structure-enhancement relationship based on maximum enhancement (Emax)
SA Ibrahim, SK Li - Journal of pharmaceutical sciences, 2009 - Elsevier
… effects, (b) the relationship between the potencies and lipophilicities of these enhancers, and
(c) the feasibility of using enhancer solubility in … alkyl chain length up to C9-12 and beyond …
(c) the feasibility of using enhancer solubility in … alkyl chain length up to C9-12 and beyond …
Time dependence of the enhancement effect of chemical enhancers: molecular mechanisms of enhancing kinetics
X Liu, P Quan, S Li, C Liu, Y Zhao, Y Zhao… - Journal of Controlled …, 2017 - Elsevier
… and the length of the hydrophobic tails. Moreover, chemical … The solubility parameter of the
enhancers was calculated using … A similar solubility parameter meant a good miscibility to …
enhancers was calculated using … A similar solubility parameter meant a good miscibility to …
Influences of alkyl group chain length and polar head group on chemical skin permeation enhancement
KS Warner, SK Li, WI Higuchi - Journal of pharmaceutical sciences, 2001 - Elsevier
… solubility, and this preparation was used in our solubility studies. The CS solubility ratios (solubility
in enhancer ÷ solubility in … modest effect of the enhancer alkyl group chain length on …
in enhancer ÷ solubility in … modest effect of the enhancer alkyl group chain length on …
Formulation possibilities of a weak base with a narrow solubility range
M Venczel, I Szvoboda, B Podányi… - Crystal growth & …, 2012 - ACS Publications
… Cremophor ELP as a solubility enhancer, surfactant, and co-… -400 spectrometer using 30
pulse length and 10 s relaxation … is purely a solubility enhancement effect due to addition of …
pulse length and 10 s relaxation … is purely a solubility enhancement effect due to addition of …
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