Advances in nutraceutical delivery systems: From formulation design for bioavailability enhancement to efficacy and safety evaluation

RFS Gonçalves, JT Martins, CMM Duarte… - Trends in Food Science …, 2018 - Elsevier
… In the present review the recent innovations regarding the formulation and design of bio-based
micro and nano-delivery systems to encapsulate nutraceuticals is discussed; it also gives …

Novel topical formulation for ischemic chronic wounds. Technological design, quality control and safety evaluation

CA Cabrera, AN Ramos, MH Loandos… - Pharmaceutical …, 2016 - Taylor & Francis
… to design a pharmaceutical dosage form by using LAPS as an active pharmaceutical ingredient
(API), to ensure its quality and to evaluate safety … therapeutic efficacy of LAPS in humans. …

[HTML][HTML] Optimal design, characterization and preliminary safety evaluation of an edible orodispersible formulation for pediatric tuberculosis pharmacotherapy

N Matawo, OA Adeleke, J Wesley-Smith - International Journal of …, 2020 - mdpi.com
… food or drink without any assessment of its impact on safety and efficacy [13,15,20]. This
may potentially lead to inaccurate dosing, resulting in reduced efficacy or adverse effects often …

Efficacy, safety, and formulation issues of the combined vaccines

SH Tafreshi - Expert Review of Vaccines, 2020 - Taylor & Francis
… Briefly, despite progress in the post-licensure safety assessment of the vaccines by designing
and implementing different passive and active post-licensure surveillance systems (such …

Preclinical efficacy and safety of herbal formulation for management of wounds

PE Ogwang, J Nyafuono, M Agwaya, F Omujal… - African health …, 2011 - ajol.info
… In this study, Jena herbal formulation significantly … good safety profile in experimental animals
and better efficacy than neomycin. We therefore recommend that the herbal formulation be …

Efficacy and safety assessment of a novel once-daily tablet formulation of tramadol: a randomised, controlled study versus twice-daily tramadol in patients with …

G Mongin, V Yakusevich, A Köpe, N Shostak… - Clinical drug …, 2004 - Springer
… to evaluate the analgesic efficacy (over a full 24-hour period) and safety profile of a new
tramadol OAD formulation (… This required that the new formulation, using a once-daily dosing …

MF59 design and evaluation of a safe and potent adjuvant for human vaccines

G Ott, GL Barchfeld, D Chernoff… - … design: the subunit and …, 1995 - Springer
… an adjuvant for efficacy, we undertook the development of a safe and efficacious adjuvant
suitable for widespread human administration. Vaccines formulated with aluminum salts (alum)…

Comparative clinical efficacy and safety of a novel controlled‐release oxycodone formulation and controlled‐release hydromorphone in the treatment of cancer pain

NA Hagen, N Babul - … Journal of the American Cancer Society, 1997 - Wiley Online Library
… the clinical efficacy and safety of a novel oxycodone formulation with … Design The study
was a double-blind, randomized, two-way crossover evaluation of the clinical efficacy and safety

Ocular disposition, pharmacokinetics, efficacy and safety of nanoparticle-formulated ophthalmic drugs

HZ Bu, HJ Gukasyan, L Goulet, XJ Lou… - Current drug …, 2007 - ingentaconnect.com
… of ophthalmic drugs formulated in … efficacy and safety of the nanoparticle-formulated
ophthalmic drugs are specifically addressed. Information and discussions summarized in this review

[HTML][HTML] Mini-tablets: A valid strategy to combine efficacy and safety in pediatrics

G Zuccari, S Alfei, D Marimpietri, V Iurilli, P Barabino… - Pharmaceuticals, 2022 - mdpi.com
… This review deals with the different approaches that may be applied to develop mini-tablets
intended for pediatrics with a focus on the safety of excipients. Alongside the conventional …