[PDF][PDF] Solubility enhancement techniques

VR Vemula, V Lagishetty, S Lingala - International journal of …, 2010 - Citeseer
soluble drugs often require high doses in order to reach therapeutic plasma concentrations
after oral administration. Low aqueous solubility is … basic with poor aqueous solubility. Hence …

Enhancing the aqueous solubility of curcumin at acidic condition through the complexation with whey protein nanofibrils

M Mohammadian, M Salami, S Momen, F Alavi… - Food …, 2019 - Elsevier
… system for improving the aqueous solubility of curcumin at acidic … in the literature on enhancing
the aqueous solubility and … novel nanocarriers for enhancing the solubility of curcumin as …

[PDF][PDF] Solubility enhancement technique: a review

S Jagtap, C Magdum, D Jadge… - Journal of pharmaceutical …, 2018 - academia.edu
… are poor aqueous soluble, hydrophobic. The solubility, property of the drugs becomes one
of the most challenging aspects in formulation development. Poor aqueous solubility results …

Comparison of pharmaceutical nanoformulations for curcumin: enhancement of aqueous solubility and carrier retention

IE Allijn, RM Schiffelers, G Storm - International journal of pharmaceutics, 2016 - Elsevier
… In this study we aimed to tackle this aqueous solubility and carrier retention challenge of …
Altogether, tested nanoparticles do solve the aqueous insolubility problem of curcumin, …

Solubility and dissolution enhancement strategies: current understanding and recent trends

S Jain, N Patel, S Lin - Drug development and industrial pharmacy, 2015 - Taylor & Francis
… The results indicated that adefovir dipivoxil-saccharin co-crystal enhanced the aqueous
solubility almost three times than that of adefovir dipivoxil. This is due to the fact that when …

Enhancement in aqueous solubility of mefenamic acid using micellar solutions of various surfactants

I Ullah, MK Baloch, I Ullah, M Mustaqeem - Journal of Solution Chemistry, 2014 - Springer
… A number of studies have been carried out in order to increase the solubility of a substrate
by using surfactants [21]. In the present study, the aqueous solubility enhancements of …

Solubility enhancement techniques with special emphasis on hydrotrophy

P Jain, A Goel, S Sharma, M Parmar - International Journal of …, 2010 - ijppronline.com
… used to enhance the aqueous solubility. The ability to increase aqueous solubility can thus
be a … Hydrotropy is one of the solubility enhancement techniques which enhance solubility to …

Exploration on the drug solubility enhancement in aqueous medium with the help of endo-functionalized molecular tubes: a computational approach

R Paul, S Paul - Physical Chemistry Chemical Physics, 2021 - pubs.rsc.org
… Here, we have focused on enhancing drug solubilization in an aqueous medium by using …
supramolecular receptors for drug solubilization in an aqueous medium. Details of these two …

[PDF][PDF] Various techniques for solubility enhancement: An overview

S Kumar, P Singh - The Pharma Innovation, 2016 - researchgate.net
… Low aqueous solubility is the major problem encountered with formulation development
of new chemical entities as well as for the generic development. Among all newly discovered …

Aqueous solubility enhancement through engineering of binary solid composites: pharmaceutical applications

MD Moore, PLD Wildfong - Journal of Pharmaceutical Innovation, 2009 - Springer
… The enhanced aqueous solubility gained through eutectic formation is often attributed (in
the pharmaceutical literature) to the lower temperature of fusion of the solidified material [31]. A …