Antidepressants in breast milk; comparative analysis of excretion ratios

G Schoretsanitis, M Augustin… - Archives of Women's …, 2019 - Springer
… For all compounds, M/P ratios were above one, reflecting higher milk than blood drug … We
then compared the C/D ratios for serum and milk as well as the M/P ratios between the three …

Drug excretion into breast milk—overview

S Ito, A Lee - Advanced drug delivery reviews, 2003 - Elsevier
… infants)=[A×(milk-to-plasma ratio)/CL i ]×100, where A is the average milk intake (eg, 150 ml
… per min), the milk-to-plasma ratio is the ratio of the drug concentration in breast milk to that in …

Determinants and consequences of drug excretion in breast milk

JT Wilson - Drug metabolism reviews, 1983 - Taylor & Francis
… of terms which apply to breast milk and maternal elimination. R is the M /P ratio and & is
the milk flow. … Breast milk excretion of PCBs is directly proportional to milk fat content. …

Excretion of antihypertensive medication into human breast milk: a systematic review

KS Beardmore, JM Morris… - Hypertension in …, 2002 - Taylor & Francis
… found that the milk to plasma (M/P) ratios varied widely … excretory properties of a drug into
breastmilk are often presented as the breastmilk to maternal plasma drug concentration ratio

Excretion of fluvoxamine in breast milk.

S Wright, S Dawling, JJ Ashford - British journal of clinical …, 1991 - ncbi.nlm.nih.gov
… active) are lipid-soluble and are excreted in breast milk. For this reason most manufacturers'
… The use of the milk to plasma-AUC ratio would give a better indication of the average milk to …

Excretion of citalopram in breast milk

O Spigset, L Carleborg, R Öhman… - British journal of …, 1997 - Wiley Online Library
… Results Milk/serum concentration ratios based on single … Serum and pre-feed breast milk
samples were obtained … weight of 64 kg, inhibitors are excreted in breast milk [2–4], but …

Excretion of metformin into breast milk and the effect on nursing infants

GG Briggs, PJ Ambrose, MP Nageotte… - Obstetrics & …, 2005 - journals.lww.com
… The mean milk:plasma ratio, milk drug concentration over the … There were wide ranges in
metformin excretion, which is … -state milk:plasma ratios in 3 breastfeeding women receiving …

Cyclosporine excretion into breast milk

ME Moretti, M Sgro, DW Johnson, RS Sauve… - …, 2003 - journals.lww.com
… Cyclosporine is excreted into human milk with milk-to-maternal serum concentration ratios
of less than one (from 0.17 to 0.4) ( 2,11,12 ). In contrast, our results in patient 1 show that …

Excretion of paroxetine into breast milk

R Ohman, S Hagg, L Carleborg… - Journal of Clinical …, 1999 - psychiatrist.com
… Results: The mean milk/serum concentration ratios in the first … seventh subject, the milk/serum
concentration ratio was 0.69 at … The mean increase in milk paroxetine concentrations from …

Anaesthetic agents and excretion in breast milk

O Spigset - Acta anaesthesiologica scandinavica, 1994 - Wiley Online Library
… agents and their excretion into breast milk; it presents the … sparse information about breast
milk excretion and even less … plasma and breast milk were parallel, with an M/Pratio of 2.45…