Air pollution and DNA methylation: effects of exposure in humans

CF Rider, C Carlsten - Clinical epigenetics, 2019 - Springer
… that air pollution exposure modulates the epigenetic mark, DNA methylation (DNAm), and …
DNAm after exposure. Effects of air pollution on DNAm have been observed across the human

Environmental influences on the epigenome: exposure-associated DNA methylation in human populations

EM Martin, RC Fry - Annual review of public health, 2018 - annualreviews.org
… (CpG) DNA methylation, and noncoding … DNA methylation alterations in humans assessed
in relation to prenatal environmental exposures, as well as studies of chronic adult exposure. …

Biological embedding of early‐life exposures and disease risk in humans: a role for DNA methylation

CA Demetriou, K van Veldhoven… - European journal of …, 2015 - Wiley Online Library
… This review focuses on DNA methylation as this is the most … DNA methylation involves the
addition of a methyl group to the 5th carbon of the pyrimidine ring, the majority of methylated

Association of global DNA methylation and global DNA hydroxymethylation with metals and other exposures in human blood DNA samples

M Tellez-Plaza, W Tang, Y Shang… - Environmental …, 2014 - ehp.niehs.nih.gov
… related to DNA methylation and hydroxymethylation levels, we examined the association
of baseline metal exposure biomarkers with visit 3 global DNA methylation and global DNA

Rapid DNA methylation changes after exposure to traffic particles

A Baccarelli, RO Wright, V Bollati… - American journal of …, 2009 - atsjournals.org
… Our data show that environmental exposures may operate on DNA methylation over a
similar time frame, with effects from particles that were significant even in association with the …

DNA methylation–based biomarkers of environmental exposures for human population studies

JC Nwanaji-Enwerem, E Colicino - Current environmental health reports, 2020 - Springer
exposures or limited access technology. We emphasize the crucial role of the individual
DNA methylation … Future research can cautiously leverage these DNA methylation–based …

DNA methylation: conducting the orchestra from exposure to phenotype?

FAD Leenen, CP Muller, JD Turner - Clinical epigenetics, 2016 - Springer
Methylation changes in the NR3C1 CpG island alters the NR3C1 transcription and …
characteristically small DNA methylation changes, the ever-growing roles of DNA methylation and …

Multigenerational epigenetic inheritance in humans: DNA methylation changes associated with maternal exposure to lead can be transmitted to the grandchildren

A Sen, N Heredia, MC Senut, S Land, K Hollocher… - Scientific reports, 2015 - nature.com
… BLL correlate with altered DNA methylation at 564 loci in … exposure during pregnancy
affects the DNA methylation status of the fetal germ cells, which leads to altered DNA methylation

DNA methylation differences after exposure to prenatal famine are common and timing-and sex-specific

EW Tobi, LH Lumey, RP Talens… - Human molecular …, 2009 - academic.oup.com
… operative in humans; periconceptional exposure to famine was associated with a decrease
in DNA methylation of the insulin-like growth factor 2 ( IGF2 ) differentially methylated region (…

DNA methylation alterations in response to pesticide exposure in vitro

X Zhang, AD Wallace, P Du, WA Kibbe… - Environmental and …, 2012 - Wiley Online Library
… ) induces DNA methylation alterations in vitro. We conducted genome-wide DNA methylation
analyses on DNA samples obtained from the human hematopoietic K562 cell line exposed