Tissue‐derived extracellular vesicles in cancers and non‐cancer diseases: present and future

SR Li, QW Man, X Gao, H Lin, J Wang… - … of Extracellular …, 2021 - Wiley Online Library
… Herein, we summarize the latest advances in Ti-EVs for cancers and non-cancer diseases.
… isolation and characterization between cancers and non-cancer diseases are reviewed and …

The role of extracellular vesicles in the progression of neurodegenerative disease and cancer

KM Candelario, DA Steindler - Trends in molecular medicine, 2014 - cell.com
… We propose that neurodegenerative diseases and cancer share a common route of transport
of disease-related proteins and nucleic acids that could mirror normal neurocytological …

Extracellular vesicles in cancer—implications for future improvements in cancer care

R Xu, A Rai, M Chen, W Suwakulsiri… - Nature reviews Clinical …, 2018 - nature.com
… shift whereby cancer is now considered more than a disease defined by molecular (genetic
and epigenetic) events within a cell and is also considered an ‘ecological disease’ that is …

The evolving translational potential of small extracellular vesicles in cancer

A Möller, RJ Lobb - Nature Reviews Cancer, 2020 - nature.com
Cancer-derived extracellular vesicles (EVs) are regarded as having promising potential to
be used as therapeutics and disease biomarkers. Mechanistically, EVs have been shown to …

Therapeutically harnessing extracellular vesicles

L Cheng, AF Hill - Nature Reviews Drug Discovery, 2022 - nature.com
… the roles of EVs in the pathology of various diseases such as cancer, neurodegenerative
diseases and cardiovascular disease 22 . The pathological capability of EVs is acquired from …

Tumor-derived extracellular vesicles: reliable tools for Cancer diagnosis and clinical applications

R Rahbarghazi, N Jabbari, NA Sani, R Asghari… - Cell Communication and …, 2019 - Springer
… release small vesicles known as extracellular vesicles (EVs) into the extracellular milieu. EVs
… in the field of clinical application of EVs in various diseases such as cancers. In the case of …

Extracellular vesicles as mediators of cancer disease and as nanosystems in theranostic applications

R Burgos-Ravanal, A Campos, MC Díaz-Vesga… - Cancers, 2021 - mdpi.com
… 9.8 million cancer-related deaths were reported worldwide. In the last 20 years, it has become
apparent that small vesicles released by cancer cells, referred to as extracellular vesicles (…

Extracellular vesicles in cancer therapy

SE Wang - Seminars in cancer biology, 2022 - Elsevier
… The past decade has witnessed a rapid growth of research and technology development
related to extracellular vesicles (EVs). Secretion of EVs is a fundamental and evolutionarily …

Extracellular vesicles–vehicles that spread cancer genes

J Rak, A Guha - Bioessays, 2012 - Wiley Online Library
… Introduction – cooperation versus competition in the ‘world’ of cancer cells Cancer is
generally viewed as a disease of mutant genes 1, 2. This is often taken to imply that oncogenic …

[HTML][HTML] Role of extracellular membrane vesicles in the pathogenesis of various diseases, including cancer, renal diseases, atherosclerosis, and arthritis

HC Anderson, D Mulhall, R Garimella - Laboratory investigation, 2010 - Elsevier
… The same pattern of pathological mineral initiation by extracellular plasma membrane-… ,
calcifying extracellular vesicles are derived not only from exfoliated surface vesicles but also from …