Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance

S Maacha, AA Bhat, L Jimenez, A Raza, M Haris… - Molecular cancer, 2019 - Springer
… Inhibition of extracellular vesicles secretion, and thus of the transfer of oncogenic molecules…
tumor growth and drug resistance. This review focuses on the role of extracellular vesicles in …

[HTML][HTML] Extracellular vesicles and anti-cancer drug resistance

N Mc Namee, L O'Driscoll - Biochimica et Biophysica Acta (BBA)-Reviews …, 2018 - Elsevier
vesicles were studied when they remained intracellular, so were not extracellular vesicles
… This study reported that a variant of MCF-7 cell line with 20-fold resistance to mitoxantrone (…

The role of extracellular vesicles in the hallmarks of cancer and drug resistance

CPR Xavier, HR Caires, MAG Barbosa, R Bergantim… - Cells, 2020 - mdpi.com
drug resistant cells. A timely and comprehensive understanding of how tumor EVs facilitate
tumor initiation, progression, metastasis and drug resistance … term “extracellular vesicles” (EVs…

Mechanisms of drug resistance in cancer: the role of extracellular vesicles

P Samuel, M Fabbri, DRF Carter - Proteomics, 2017 - Wiley Online Library
… of resistance is the role of intercellular communication, and in particular the role of extracellular
vesicles (EVs) which will be the focus of this review. EVs are small vesicular structures …

Extracellular vesicles in cancer drug resistance: roles, mechanisms, and implications

Q Yang, J Xu, J Gu, H Shi, J Zhang, J Zhang… - Advanced …, 2022 - Wiley Online Library
… to deliver drugs for overcoming drug resistance in cancer … drug resistance are summarized.
The preclinical studies on using EVs in monitoring and overcoming cancer drug resistance

The role of extracellular vesicles in the transfer of drug resistance competences to cancer cells

CPR Xavier, DC Belisario, R Rebelo, YG Assaraf… - Drug Resistance …, 2022 - Elsevier
… Representation of intercellular transfer of drug resistance mediated by extracellular
vesicles (EVs). Drug-resistant (donor) cells may release different types of EVs (exosomes or/and …

Intercellular transfer of cancer drug resistance traits by extracellular vesicles

D Sousa, RT Lima, MH Vasconcelos - Trends in molecular medicine, 2015 - cell.com
… transfer of drug resistance from drug-resistant to drug-… intercellular transfer of drug resistance;
namely, drug-efflux pumps, … the intercellular transfer of drug resistance mediated by EVs. …

Extracellular vesicles: emerging modulators of cancer drug resistance

F Fontana, E Carollo, GE Melling, DRF Carter - Cancers, 2021 - mdpi.com
Drug resistance still represents the main reason for therapy failure in cancer patients. In the
last decade, extracellular vesicles … cancer drug resistance are described in this review article. …

Extracellular vesicles as a novel source of biomarkers in liquid biopsies for monitoring cancer progression and drug resistance

MH Vasconcelos, HR Caires, A Ābols… - Drug Resistance …, 2019 - Elsevier
… phenotypic traits and drug-resistant phenotypes to other cancer … of tumor burden and drug
resistance. In this review, we have … emergence or progression of drug resistance. Furthermore, …

The roles of extracellular vesicles in gastric cancer development, microenvironment, anti-cancer drug resistance, and therapy

T Huang, C Song, L Zheng, L Xia, Y Li, Y Zhou - Molecular cancer, 2019 - Springer
Extracellular vesicles (EVs) are secreted by nearly almost cell types and released to the
extracellular … , immune response, drug resistance or communicated with microenvironment in GC…