Tumor-derived extracellular vesicles: Regulators of tumor microenvironment and the enlightenment in tumor therapy

J Chen, X Fei, J Wang, Z Cai - Pharmacological Research, 2020 - Elsevier
In recent decades, extracellular vesicles (EVs) have been proven to establish an important
bridge of communication between cells or cells and their microenvironment. It is well known …

[HTML][HTML] Tumor-derived extracellular vesicles regulate cancer progression in the tumor microenvironment

Q Bao, Q Huang, Y Chen, Q Wang, R Sang… - Frontiers in molecular …, 2022 - frontiersin.org
… As a result, tumor-derived EVs can deliver molecules to remodel the tumor microenvironment,
thereby influencing cancer progression. On the one hand, tumor-derived EVs reprogram …

[HTML][HTML] Extracellular vesicles in the tumor microenvironment: old stories, but new tales

L Han, EWF Lam, Y Sun - Molecular cancer, 2019 - Springer
… and a regulator of angiogenesis and metastasis) are correlated with the genetic status of
cancer cells, such as an activated KRAS oncogene or a loss-of-function mutation of the p53 …

Extracellular vesicles as modulators of the cancer microenvironment

J Webber, V Yeung, A Clayton - Seminars in cell & developmental biology, 2015 - Elsevier
… been growing interests in the potential roles of extracellular vesicles (EV) in many of the …
distinct functions for extracellular vesicles in modulating the microenvironment with examples …

[HTML][HTML] Extracellular vesicles and their roles in the tumor immune microenvironment

A Reale, T Khong, A Spencer - Journal of Clinical Medicine, 2022 - mdpi.com
… , EVs are able to promote the formation of a supportive tumor microenvironment (TME) and
(… Treatment with these EVs reduced tumor growth via regulation of the miR-765/PLP2 axis. …

[HTML][HTML] How cancer cells dictate their microenvironment: present roles of extracellular vesicles

Y Naito, Y Yoshioka, Y Yamamoto, T Ochiya - Cellular and Molecular Life …, 2017 - Springer
vesicles, termed extracellular vesicles (EVs), served as a regulatory agent in the intercellular
communication of cancer. … These cells within the tumor microenvironment and cancer cells …

[HTML][HTML] Extracellular vesicles in the tumour microenvironment: eclectic supervisors

C Cavallari, G Camussi, MF Brizzi - International journal of molecular …, 2020 - mdpi.com
… The tumour microenvironment (TME) plays a crucial role in the regulation of cell survival
and growth by providing inhibitory or stimulatory signals. Extracellular vesicles (EV) represent …

[HTML][HTML] Extracellular vesicles in the tumor immune microenvironment

P Hou, H Chen - Cancer letters, 2021 - Elsevier
… in the tumor microenvironment, as mentioned above, immune cell-derived extracellular
vesicles have also been shown to regulate the activation of immune responses, resulting in …

[HTML][HTML] Extracellular vesicles are key regulators of tumor neovasculature

N Kuriyama, Y Yoshioka, S Kikuchi… - Frontiers in Cell and …, 2020 - frontiersin.org
tumor cells and endothelial cells via extracellular vesicles. This … tumor microenvironment
(TME) and extracellular vesicles (EVs). Tumor cells under hypoxia produce more extracellular

[HTML][HTML] Extracellular vesicles-mediated intercellular communication: roles in the tumor microenvironment and anti-cancer drug resistance

S Maacha, AA Bhat, L Jimenez, A Raza, M Haris… - Molecular cancer, 2019 - Springer
… shifts over to be tumor promotive [2]. Cells found in the tumor microenvironment (TME) have
been recognized as key regulators of tumor promotion by providing mitogenic growth factors…