… fluid homeostasis and its function is important to understanding fluid administration in patients
with severe sepsis and septic … described the traditional view that fluid was filtered at the …

… Fluid resuscitation of severe sepsis may consist of natural or artificial colloids or crystalloids.
Fluid challenge should be administered and repeated based on response (increase in …

… Despite the limited evidence, such is the hold of the fluid bolus resuscitation paradigm on …
fluid bolus resuscitation should be a cornerstone of the management of severe sepsis or septic …

… Patients with severe sepsis and septic shock who do not receive the recommended 30
mL/kg IV fluid bolus within the first 3 hours of severe sepsis or septic shock diagnosis were at …

… compared albumin to several different fluids including normal saline, lactated … in septic,
severely septic, or septic shock patients resuscitated with albumin compared with the other fluids (…

… published on the type of fluid used in the resuscitation of patients with sepsis. The primary
goal of … intravenous fluid for the resuscitation of patients with severe sepsis and septic shock. …

… ill patients with severe sepsis or septic shock as defined by the investigators and who required
fluid resuscitation (defined as the administration of a bolus of intravenous fluid exceeding …

… Similarly, in a retrospective study of 2632 ICU patients with severe sepsis and septic shock,
each 1 L increase in cumulative fluid balance at 72 hours was independently associated with …

… Following initial resuscitation, however, fluid boluses often fail to … of fluids in early and
later sepsis; show that much fluid therapy is clinically ineffective in patients with severe sepsis; …

… In conclusion, we have demonstrated the average day 1 fluid administration in patients
with severe sepsis and septic shock, treated in a broad spectrum of hospitals in the USA, …