Salmeterol and fluticasone propionate combined in a new powder inhalation device for the treatment of asthma: a randomized, double-blind, placebo-controlled trial

M Kavuru, J Melamed, G Gross, C LaForce… - Journal of Allergy and …, 2000 - Elsevier
… and fluticasone propionate powder in the Diskus inhalation device offered superior asthma
control compared with administration of either salmeterol or fluticasone propionate alone. …

Salmeterol/fluticasone propionate in a single inhaler device versus theophylline+ fluticasone propionate in patients with COPD

M Cazzola, P Noschese, S Centanni, P Santus… - Pulmonary …, 2004 - Elsevier
Study objectives. The aim of this study was to compare the relative efficacy in terms of
improvement in symptoms and lung function of salmeterol/fluticasone propionate (SLM/FP) …

Fluticasone propionate plasma concentration and systemic effect: effect of delivery device and duration of administration

…, SJ Szefler, Asthma Clinical Research Network… - Journal of allergy and …, 2005 - Elsevier
fluticasone concentrations are significantly greater when the drug is inhaled from an MDI
than from a DPI delivery device. … showing that DPI delivery devices generate particles with a …

Inhaler device selection: special considerations in elderly patients with chronic obstructive pulmonary disease

R Barrons, A Pegram, A Borries - American Journal of Health …, 2011 - academic.oup.com
… controller medications, such as fluticasone propionate–salmeterol xinafoate (Advair, … (eg,
the annual cost for combination fluticasone propionate 250 μg–salmeterol xinafoate 50 μg …

… dose delivery of fluticasone propionate from a small valved holding chamber, a compact breath actuated integrated vortex device and a metered dose inhaler

A Nair, D Menzies, M Barnes, P Burns… - British journal of …, 2008 - Wiley Online Library
… • The lung bioavailability of inhaled fluticasone propionate is dependant on respirable dose
delivery, and hence the performance of inhaler devices can be quantified by measuring the …

The DiskusTM: a review of its position among dry powder inhaler devices

H Chrystyn - International journal of clinical practice, 2007 - Wiley Online Library
… of inhaled drug is now formulated as a pMDI. This small and unobtrusive device remains the
most commonly used inhalation device … salmeterol (37), fluticasone propionate (38) and the …

… of USP induction ports, glass sampling apparatus, and inhaler device resistance on aerodynamic patterns of fluticasone propionate–loaded engineered mannitol …

P Mehta, C Bothiraja, S Kadam, A Pawar - AAPS PharmSciTech, 2019 - Springer
… uniformity of fluticasone propionate (FP) dry powder inhaler (… Additionally, commercially
available two DPI inhaler devices … IP with the Breezhaler® device was significantly higher (1.32-…

Pharmacokinetics of fluticasone propionate inhaled via the Diskhaler® and Diskus® powder devices in healthy volunteers

AE Mackie, JE McDowall, C Falcoz, P Ventresca… - Clinical …, 2000 - Springer
… in healthy volunteers of inhaled fluticasone propionate (FP) administered as a … devices,
and the pharmacokinetics of inhaled FP after repeated administration via the Diskhaler® device

… and safety of mometasone furoate dry powder inhaler vs fluticasone propionate metered-dose inhaler in asthma subjects previously using fluticasone propionate

A Wardlaw, P Larivee, J Eller, DW Cockcroft… - … of Allergy, Asthma & …, 2004 - Elsevier
device delivered mometasone furoate, 400 g per inhalation, and the MDI device delivered
fluticasone propionate, 125 g per inhalation. … device with previous fluticasone propionate MDI …

Effectiveness of fluticasone propionate and salmeterol combination delivered via the Diskus device in the treatment of chronic obstructive pulmonary disease

DA Mahler, P Wire, D Horstman, CN Chang… - American journal of …, 2002 - atsjournals.org
… of combining an inhaled corticosteroid, fluticasone propionate (F), with an inhaled long-…
), or placebo twice daily via the Diskus device for 24 weeks. A significantly greater increase in …