Clinical significance of the expression of DNA methyltransferase proteins in gastric cancer
J Yang, X Wei, Q Wu, Z Xu, D Gu… - Molecular …, 2011 - spandidos-publications.com
… Although overexpression of DNMTs is not equal to the aberrant DNA methylation pattern in
gastric cancer, our findings, such as the distribution of DNMTs and the correlations between …
gastric cancer, our findings, such as the distribution of DNMTs and the correlations between …
The expression and clinical significance of DNA methyltransferase proteins in human gastric cancer
WJ Ding, JY Fang, XY Chen, YS Peng - Digestive diseases and sciences, 2008 - Springer
… of DNA methyltransferase (DNMT) proteins in gastric cancer (GC… expression of the 3 DNMTs
in gastric tissues. We discovered that … Therefore, DNMT overexpression is involved in gastric …
in gastric tissues. We discovered that … Therefore, DNMT overexpression is involved in gastric …
MiR-148a regulates MEG3 in gastric cancer by targeting DNA methyltransferase 1
J Yan, X Guo, J Xia, T Shan, C Gu, Z Liang, W Zhao… - Medical oncology, 2014 - Springer
… MiR-148a can suppress gastric tumorigenesis through regulating the expression of … as
DNA methyltransferase 1(DNMT-1). We examined the expression of MEG3 in 52 gastric cancer …
DNA methyltransferase 1(DNMT-1). We examined the expression of MEG3 in 52 gastric cancer …
DNA methyltransferase 1 as a predictive biomarker and potential therapeutic target for chemotherapy in gastric cancer
K Mutze, R Langer, F Schumacher, K Becker… - … journal of cancer, 2011 - Elsevier
… may influence the effect of DNA-damaging drugs. We examined the prognostic and predictive
impact of DNA methyltransferase (DNMT) 1 and 3b expression in gastric carcinomas (GC) …
impact of DNA methyltransferase (DNMT) 1 and 3b expression in gastric carcinomas (GC) …
DNA methyltransferases and gastric cancer: insight into targeted therapy
S Fattahi, M Golpour, F Amjadi-Moheb… - …, 2018 - Taylor & Francis
… by DNA methyltransferases (DNMTs) are a well-characterized epigenetic hallmark in gastric
cancer. The reversible nature of epigenetic alterations and central role of DNA methylation …
cancer. The reversible nature of epigenetic alterations and central role of DNA methylation …
… DNA methyltransferase 1 (DNMT1) protein expression correlates significantly with poorer tumor differentiation and frequent DNA hypermethylation of multiple CpG …
T Etoh, Y Kanai, S Ushijima, T Nakagawa… - The American journal of …, 2004 - Elsevier
… gastric and colorectal cancers. However, most previous analyses concerning DNMT1 expression
in human cancers … To our knowledge, DNMT1 protein expression in gastric cancers has …
in human cancers … To our knowledge, DNMT1 protein expression in gastric cancers has …
Accumulation of DNA methylation is associated with tumor stage in gastric cancer
N Oue, Y Mitani, J Motoshita… - Cancer …, 2006 - Wiley Online Library
… The authors purpose in this study was to clarify the difference in terms of clinicopathologic
features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG …
features between gastric cancer (GC) with high numbers of DNA methylated genes and CpG …
MicroRNA-148a is silenced by hypermethylation and interacts with DNA methyltransferase 1 in gastric cancer
A Zhu, J Xia, J Zuo, S Jin, H Zhou, L Yao, H Huang… - Medical oncology, 2012 - Springer
… -148a is inactivated by DNA hypermethylation of promoter region in gastric cancer, which is
… in gastric cancer, and this may in turn result in over-expression of DNMT1 and promote DNA …
… in gastric cancer, and this may in turn result in over-expression of DNMT1 and promote DNA …
[HTML][HTML] Risk-association of DNA methyltransferases polymorphisms with gastric cancer in the Southern Chinese population
XX Yang, XQ He, FX Li, YS Wu, Y Gao, M Li - International journal of …, 2012 - mdpi.com
… DNA hypomethylation and/or hypermethylation are presumed to be early … more DNA
methyltransferases (DNMTs) have been suggested to play roles in carcinogenesis of gastric cancer (…
methyltransferases (DNMTs) have been suggested to play roles in carcinogenesis of gastric cancer (…
[HTML][HTML] Antitumor Effect of Simvastatin in Combination With DNA Methyltransferase Inhibitor on Gastric Cancer via GSDME-Mediated Pyroptosis
… due to promoter hypermethylation is associated with gastric cancer (GC), which is
confirmed … (DOX)- inducible Tet-on system or DNA methyltransferase inhibitor 5-Aza-2′-deoxycytidine …
confirmed … (DOX)- inducible Tet-on system or DNA methyltransferase inhibitor 5-Aza-2′-deoxycytidine …
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