[HTML][HTML] Gefitinib or chemotherapy for non–small-cell lung cancer with mutated EGFR
M Maemondo, A Inoue, K Kobayashi… - … England Journal of …, 2010 - Mass Medical Soc
… studies of gefitinib therapy in patients with advanced non–small-cell lung cancer and
EGFR … We then undertook a phase 3 study comparing gefitinib and standard carboplatin–paclitaxel …
EGFR … We then undertook a phase 3 study comparing gefitinib and standard carboplatin–paclitaxel …
[HTML][HTML] EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
… with EGFR-mutant, gefitinib-responsive, advanced non–small-cell lung cancer who had a …
during treatment with gefitinib. The DNA sequence of the EGFR gene in his tumor biopsy …
during treatment with gefitinib. The DNA sequence of the EGFR gene in his tumor biopsy …
Review of the treatment of non-small cell lung cancer with gefitinib
T Araki, H Yashima, K Shimizu… - Clinical Medicine …, 2012 - journals.sagepub.com
… of gefitinib for advanced non-small cell lung cancer with epidermal growth factor receptor
mutations: results of the West Japan Thoracic Oncology Group trial (WJOTG0403). Br J Cancer. …
mutations: results of the West Japan Thoracic Oncology Group trial (WJOTG0403). Br J Cancer. …
Predictors of the Response to Gefitinib in Refractory Non–Small Cell Lung Cancer
KS Kim, JY Jeong, YC Kim, KJ Na, YH Kim, SJ Ahn… - Clinical Cancer …, 2005 - AACR
… Gefitinib, an epidermal growth factor receptor (EGFR) … 20% in refractory non–small cell lung
carcinoma. Although female … Seventy patients with relapsed non–small cell lung carcinoma …
carcinoma. Although female … Seventy patients with relapsed non–small cell lung carcinoma …
Clinical benefit of readministration of gefitinib for initial gefitinib-responders with non-small cell lung cancer
H Yokouchi, K Yamazaki, I Kinoshita, J Konishi… - BMC cancer, 2007 - Springer
… Gefitinib, an oral agent of epidermal growth factor receptor tyrosine kinase inhibitor, has a
… against non-small cell lung cancer (NSCLC). Several predictive factors of gefitinib sensitivity …
… against non-small cell lung cancer (NSCLC). Several predictive factors of gefitinib sensitivity …
A phase II trial of gefitinib as first-line therapy for advanced non-small cell lung cancer with epidermal growth factor receptor mutations
H Asahina, K Yamazaki, I Kinoshita, N Sukoh… - … journal of cancer, 2006 - nature.com
… In conclusion, gefitinib treatment as first-line therapy for advanced NSCLC with EGFR
mutations demonstrated promising activity and a good toxicity profile. Randomised phase III trials …
mutations demonstrated promising activity and a good toxicity profile. Randomised phase III trials …
Akt phosphorylation and gefitinib efficacy in patients with advanced non–small-cell lung cancer
F Cappuzzo, E Magrini, GL Ceresoli… - … the National Cancer …, 2004 - academic.oup.com
… to identify which patients may respond to gefitinib therapy, we evaluated the association …
NSCLC before starting gefitinib therapy and evaluated their response to gefitinib therapy. This …
NSCLC before starting gefitinib therapy and evaluated their response to gefitinib therapy. This …
[PDF][PDF] Practical management of patients with non–small-cell lung cancer treated with gefitinib
NT Shah, MG Kris, W Pao, LB Tyson… - Journal of Clinical …, 2005 - academia.edu
… in persons with lung cancer. Many of the principles of management relevant to gefitinib are
distinct … practical guidelines on the use of gefitinib in patients with non–small-cell lung cancer. …
distinct … practical guidelines on the use of gefitinib in patients with non–small-cell lung cancer. …
… in the tyrosine kinase domain of epidermal growth factor receptor is a predictive and prognostic factor for gefitinib treatment in patients with non–small cell lung cancer
TY Chou, CH Chiu, LH Li, CY Hsiao, CY Tzen… - Clinical cancer …, 2005 - AACR
… to predict the tumor response of patients receiving gefitinib for non–small cell lung cancer
(NSCLC). … kinase domain and tumor response and survival in gefitinib-treated NSCLC patients. …
(NSCLC). … kinase domain and tumor response and survival in gefitinib-treated NSCLC patients. …
Outcomes of patients with advanced non-small cell lung cancer treated with gefitinib (ZD1839,'Iressa') on an expanded access study
PA Jänne, S Gurubhagavatula, BY Yeap, J Lucca… - Lung cancer, 2004 - Elsevier
… The ongoing characterization of the molecular abnormalities in non-small-cell lung cancer
has identified potential therapeutic targets. One of these is the epidermal growth factor …
has identified potential therapeutic targets. One of these is the epidermal growth factor …