… nal mosaicism for Y-linked mutations that lead to oligospermia or azoospermia in otherwise
normal male offspring of mosaic fathers. Continued comparative studies of male genomic …

… , produce a germline and/or somatic mosaic. In hemophilia, somatic mosaicism has been …
undergoing medically assisted procreation because of the infertility of her partner, a genetic …

… to infertility may occur in younger patients. The vast majority of the infertile male population
… It appears that like women these men, that demonstrate diminished gonadal reserve, are at …

… et al. investigated 78 infertile men with primary infertility. In … XY mosaicism presents wide
range of phenotypes and can affect hormonal balance, gonadal development, growth and fertility…

… The clinician has a duty to inform the couple, where possible, of the reason for the male’s …
of the infertile male. The great progress in understanding the genetic regulation of gonadal …

… male infertility, azoospermia. In this chapter, we explore known genetic causes of male infertility
such as Klinefelter syndrome, XYY men, … inversions, mixed gonadal dysgenesis, x-linked …

… termed “idiopathic infertility”. A part from few exceptions, the only available therapy for male
factor infertility is assisted reproduction which allows conception also in severe male factor, …

… of genetic factors in male infertility is linked to postnatal alterations that can occur either in
all tissues or only in reproductive organs and spermatozoa (gonadal mosaicism). Separately, …

… However, since the oocytes were obtained from relatively young patients with fertility problems…
in female fetal gonads is that the same is not true for the male counterparts. Testicular cell …

… a larger role for postzygotic mosaicism relative to gonadal mosaicism. The presence of …
can restore fertility. In this instance, genetic testing of the sperm of male mosaic patients would …