The biology of epidermal growth factor receptor in lung cancer
GV Scagliotti, G Selvaggi, S Novello, FR Hirsch - Clinical Cancer Research, 2004 - AACR
The prognostic significance of epidermal growth factor receptor (EGFR) expression in lung
cancer and, more importantly, its ability to predict response to anti-EGFR therapies, are …
cancer and, more importantly, its ability to predict response to anti-EGFR therapies, are …
Epidermal growth factor receptor mutations in lung cancer
SV Sharma, DW Bell, J Settleman, DA Haber - Nature Reviews Cancer, 2007 - nature.com
… that target the epidermal growth factor receptor (EGFR) provide important insights for new
lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review …
lung cancer therapies, as well as for the broader field of targeted cancer therapies. We review …
[HTML][HTML] Epidermal growth factor receptor inhibition in lung cancer: status 2012
… –small-cell lung cancer (NSCLC). Epidermal growth factor receptor (EGFR) tyrosine kinase
inhibitors (TKIs) have demonstrated significantly improved tumor responses and progression-…
inhibitors (TKIs) have demonstrated significantly improved tumor responses and progression-…
Screening for epidermal growth factor receptor mutations in lung cancer
… in the epidermal growth factor receptor gene (EGFR) confer hypersensitivity to the tyrosine
kinase inhibitors gefitinib and erlotinib in patients with advanced non–small-cell lung cancer. …
kinase inhibitors gefitinib and erlotinib in patients with advanced non–small-cell lung cancer. …
[HTML][HTML] Epidermal growth factor receptor (EGFR) in lung cancer: an overview and update
G Bethune, D Bethune, N Ridgway… - Journal of thoracic …, 2010 - ncbi.nlm.nih.gov
… downstream targets is thought to yield more aggressive tumor phenotypes. Mutations in
epidermal growth factor receptor have been discovered in association with some lung cancers. …
epidermal growth factor receptor have been discovered in association with some lung cancers. …
Epidermal growth factor receptor family in lung cancer and premalignancy
WA Franklin, R Veve, FR Hirsch, BA Helfrich… - Seminars in …, 2002 - Elsevier
… , particularly overexpression of epidermal growth factor receptor (EGFR) family proteins. …
EGF and transforming growth factor alpha. Epidermal growth factor receptor overexpression is …
EGF and transforming growth factor alpha. Epidermal growth factor receptor overexpression is …
[HTML][HTML] Role of epidermal growth factor receptor in lung cancer and targeted therapies
TC Liu, X Jin, Y Wang, K Wang - American Journal of Cancer …, 2017 - ncbi.nlm.nih.gov
… In the current review, we propose to illustrate the role of EGFR group of growth factors in lung
cancer progression and metastasis. We will particularly emphasize upon the impact of well-…
cancer progression and metastasis. We will particularly emphasize upon the impact of well-…
Epidermal growth factor receptors in non-small cell lung cancer
D Veale, T Ashcroft, C Marsh, GJ Gibson… - … journal of cancer, 1987 - nature.com
… They were stained for epidermal growth factor receptor (EGFr) by means of an indirect …
growth factor receptor may play a part in the genesis or spread of lung cancers. This is the …
growth factor receptor may play a part in the genesis or spread of lung cancers. This is the …
Epidermal growth factor receptor mutations in small cell lung cancer
A Tatematsu, J Shimizu, Y Murakami, Y Horio… - Clinical Cancer …, 2008 - AACR
… growth factor receptor (EGFR) mutations occur in lung adenocarcinoma, and even rare cases
of other subtypes with this mutation, such as adenosquamous cell carcinoma… lung cancers (…
of other subtypes with this mutation, such as adenosquamous cell carcinoma… lung cancers (…
Targeting the epidermal growth factor receptor in non-small cell lung cancer
RS Herbst, PA Bunn Jr - Clinical cancer research, 2003 - AACR
… apoptosis, are in clinical development to treat lung cancer. Among these targeted
therapies are the oral, small-molecule epidermal growth factor receptor-tyrosine kinase (EGFR-TK) …
therapies are the oral, small-molecule epidermal growth factor receptor-tyrosine kinase (EGFR-TK) …
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