… Since our aim is to discover clinically applicable biomarkers from PPI network data, therefore,
we should control the size of obtained networks while providing testable experimental …

Background Hepatocellular carcinoma (HCC) is one of the most common types of cancer
worldwide. Despite several efforts to elucidate molecular mechanisms involved in this cancer, …

Hepatocellular carcinoma (HCC) is a highly malignant tumor found in the bile duct epithelial
cells, and the second most common tumor of the liver. However, the pivotal roles of most …

… (ceRNA) network and have attracted growing attention. The present study explored the
regulatory mechanisms and functional roles of lncRNAs as ceRNAs in hepatocellular carcinoma (…

… d The flowchart shows the computational algorithm of our mathematical model to identify
dynamic network biomarkers (DNBs), signalling the pre-metastatic state. e The graph illustrates …

… cascades of spatial and temporal changes in genetic networks and metabolic pathways [1]. …
on searching for network biomarkers of cancers [10–16]. Hepatocellular carcinoma (HCC) is …

… Hepatocellular carcinoma (HCC) is the major histological … methods (such as dynamic
network biomarkers, DNB) can be … based on landscape dynamic network biomarkers (L-DNB), …

… and to construct dynamic networks. Dynamic concentration analysis and network topological
… 20:5 was identified as the potential biomarker for hepatocellular carcinoma (HCC). It can be …

… biomarkers in the early detection of hepatocellular carcinoma… Therefore, constructing a
network to analyze biomarkers … –gene interaction network for biomarker identification in HCC. …

… as a dominant hazard factor for hepatocellular carcinoma (HCC) and accounts for at least …
network (PPI) was performed. The ten hub genes screened out from the PPI network were …