Facilities and methods for the high-throughput crystal structural analysis of human proteins

U Heinemann, K Büssow, U Mueller… - Accounts of chemical …, 2003 - ACS Publications
… the high-throughput crystal structure analysis of proteins (see Figure 1), leaving aside other
aspects of the Protein Structure … KMC-1: A high resolution and high flux soft x-ray beamline at …

Importance of determination of crystal quality in protein crystals when performing high-resolution structural analysis

H Koizumi, R Suzuki, M Tachibana… - Crystal Growth & …, 2016 - ACS Publications
… X-ray structural analysis. … crystal quality of a protein crystal under analysis is adequate to
obtain accurate three-dimensional structures of protein molecules for X-ray structural analyses. …

Protein crystal structure analysis from high-resolution X-ray powder-diffraction data

RB Von Dreele - Methods in enzymology, 2003 - Elsevier
Publisher Summary This chapter describes the protein crystal structure analysis from high
resolution X-Ray powder-diffraction data. Powder diffraction is the workhorse of X-ray …

High-resolution X-ray diffraction analyses of protein crystals

HM Volz, RJ Matyi - … Transactions of the Royal Society of …, 1999 - royalsocietypublishing.org
… , the accuracy of these structural analyses is adversely affected by the large number of
defects in protein crystals (McPherson 1989). Despite their benefit to the inorganic crystal-growth …

The advantages and limitations of protein crystal structures

KR Acharya, MD Lloyd - Trends in pharmacological sciences, 2005 - cell.com
Crystal structure analysis using X-ray diffraction is, in many cases, the most advanced method
available for obtaining high-resolution structural … the highest resolution data from the crystal

Protein-protein recognition: Crystal structural analysis of a barnase-barstar complex at 2.0-. ANG. resolution

AM Buckle, G Schreiber, AR Fersht - Biochemistry, 1994 - ACS Publications
… In this paper we describe the 2.0-A resolution crystal structure of a 1:1 complex between the
… The higher resolution of the present structural data allows a more detailed analysis of the …

Structural heterogeneity in protein crystals

JL Smith, WA Hendrickson, RB Honzatko, S Sheriff - Biochemistry, 1986 - ACS Publications
… as from results on the other structures at higher resolution. The resolution limits of a structure
analysis affect both the minimum population for a structural substate to be observable and …

Water–protein interactions from highresolution protein crystallography

M Nakasako - … Transactions of the Royal Society of …, 2004 - royalsocietypublishing.org
crystal structure analyses, no hydration water molecules at a distance greater than 4 Afrom
the protein … Water molecules at greater distances from the protein surface distribute randomly, …

Simulations of a protein crystal with a high resolution X-ray structure: evaluation of force fields and water models

DS Cerutti, PL Freddolino, RE Duke Jr… - The Journal of Physical …, 2010 - ACS Publications
… The high resolution of the diffraction data (0.96 Å) and the simplicity of the crystallization
to attribute any inconsistencies between the crystal structure and our simulations to artifacts of …

[图书][B] Crystal structure analysis for chemists and biologists

JP Glusker, M Lewis, M Rossi - 1996 - books.google.com
… diffraction pattern of a crystal and find experimentally, with high precision, the ar… crystal can
be obtained. Throughout this book we will illustrate results of a single crystal structure analysis