… feedback loops by epigenetic factors reinforces DNA methylation and silencing of PRC
targets with implications for development and disease states. Additional evidence for polycomb–…

… and the pathological consequences of their … DNA methylation patterns in human diseases.
It should be noted that I focus only on those diseases for which defective DNA methylation …

… Here, we review the impact of the studies on DNA methylation, the … of human diseases caused
by or involving DNA methylation … syndromic, given the pleiotropic effect of mutations on the …

… The beststudied case is of the effects of the H19/IGF-2 locus on … of DNA methylation to the
control of gene imprinting and X inactivation. In summary, the disruption of DNA methylation …

… the physiological impact of … of disease. We conducted a systematic review to critically assess
the full range of clinical associations that have been reported in relation to DNA methylation …

… metabolism, highlighting the role of DNA methylation inside this organelle and its impact
on human diseases. We also discuss the possible impact of the nuclear genetic background …

… hypermethylation. Here we review recent findings on altered DNA methylation in human
disease… regulated transcription factors are a direct effect of DNA demethylation, and comparative …

… The effects of DNA methylation on chromatin and … in DNA demethylation (DNA methylation
erasers), including TET1, TET2 and TET3. Methylcytosine-binding proteins (DNA methylation …

… analysis of DNA methylation in human diseases, including cancer and non-neoplastic diseases.
We review … DNA methylation may affect the transcription of genes in two ways. First, the …

… methylation is generally associated with gene expression. Extrinsic factors such as age,
diets and lifestyle affect DNA methylation … factors also modify DNA methylation patterns. This …