Imiquimod, a patient-applied immune-response modifier for treatment of external genital warts

KR Beutner, SK Tyring, KF Trofatter Jr… - Antimicrobial agents …, 1998 - Am Soc Microbiol
… In this study, imiquimod, an immune-response modifier, had clinically significant efficacy
in the treatment of genital warts. Complete response rates with 5% imiquimod cream were …

Treatment of genital warts with an immune-response modifier (imiquimod)

KR Beutner, SL Spruance, AJ Hougham, TL Fox… - Journal of the American …, 1998 - Elsevier
… Imiquimod is a novel immune-response modifier capable of … imiquimod for the treatment of
external genital warts. Methods: This … One hundred eight patients with external genital warts (…

[PDF][PDF] Imiquimod: a new immune response modifier for the treatment of external genital warts and other diseases in dermatology

B Berman - International journal of dermatology, 2002 - academia.edu
… the treatment of genital warts, it appears that immunological memory is stimulated after
imiquimod treatment as … In comparison to ablative treatments for common warts (eg salicylic acid, …

Immune-response modifiers: A new paradigm in the treatment of human papillomavirus

SK Tyring - Current therapeutic research, 2000 - Elsevier
… that produces a strong virus-specific immune responseimmune-response modifler,
induces local cytolcine production and reduces HPV load in patients with external genital warts

Enhancement of the innate and cellular immune response in patients with genital warts treated with topical imiquimod cream 5%

I Arany, SK Tyring, MA Stanley, MA Tomai, RL Miller… - Antiviral research, 1999 - Elsevier
Treatment with imiquimod, an immune response modifierimmune response. Imiquimod
administration was also associated with a significant decrease in viral load as measured by HPV

External genital warts: diagnosis, treatment, and prevention

DJ Wiley, J Douglas, K Beutner, T Cox… - Clinical Infectious …, 2002 - academic.oup.com
External genital warts (EGWs) are visible warts that occur in … -oncogenic human papillomavirus
(HPV) types, usually types 6 … , and imiquimod, an immune response modifier, seek to treat …

Topical immunomodulators for the treatment of external genital warts, cutaneous warts and molluscum contagiosum

UR Hengge, M Cusini - British Journal of Dermatology, 2003 - academic.oup.com
… Clinical evaluation of the immune response modifier (IRM) imiquimod for the treatment of
genital warts has included approximately 40 studies to date, with over 3400 patients, of whom …

Correlation between pretreatment levels of interferon response genes and clinical responses to an immune response modifier (Imiquimod) in genital warts

I Arany, SK Tyring, MM Brysk, MA Stanley… - Antimicrobial agents …, 2000 - Am Soc Microbiol
… used in treatment of genital warts. In clinical settings, patients responded well but wart
reduction rates varied. Our aim was to find a correlation between clinical responses and …

Imiquimod: an immune response modifier

MV Dahl - Journal of the American Academy of Dermatology, 2000 - jaad.org
… How can we bring this knowledge to help our patients with genital warts? If we could achieve
… and cytokine production, it may have wide use as treatment for a variety of benign and …

Dermal dendritic cells in anogenital warty lesions unresponsive to an immuneresponse modifier

JE Arrese, P Paquet, N Claessens… - Journal of cutaneous …, 2001 - Wiley Online Library
… Interferon (IFN) therapy was introduced in order to target HPV 11–13 but has not gained …
an immune-response modifier inducing anogenital wart regression. The same topical treatment