… targeted agents. In this review, we highlight the impact of glycosylation in cancer targeted
therapy… targeted therapy, immune checkpoints blockade therapy, and current developments on …

… on the impact of glycosylation in cancer biology and its influence in the current approaches
of targeted cancer therapies in the clinical setting. The roles of glycosylation in cancer …

… Protein glycosylation occurs mainly in the endoplasmic reticulum (ER) and the … protein
glycosylation: N-linked glycosylation (N-glycosylation) and O-linked glycosylation (O-glycosylation…

… target toxicity is a common challenge in blockage of Wnt pathway that needs to be addressed
in the development of Wnt targeting therapy… approach targeting protein glycosylation to …

… of the unglycosylated protein that mounted an elevated immune response compared to
the glycosylated protein. Alternatively, the carbohydrate may have “shielded” the protein from …

… targeted treatments available for patients with ER and HER2 positive breast cancers. Hormonal
therapies, … However, all of these targeted therapies have associated issues with acquired …

… therapeutic targets to improve the management of HCC. Here, we describe the change of
protein glycosylation … - and targeted therapies, aberrant glycosylation also impacts the efficacy …

… Protein and lipid glycosylation are vital to fundamental cellular processes. For therapeutic
strategies that target glycosylation… this effect correlates with the dose-dependent antiviral effect …

… ) oligosaccharide primary structure in recombinant proteins, an important consideration …
areas in which glycosylation can effect the therapeutic utility of recombinant proteins. Finally…

… effects of protein glycosylation on cancer immunotherapy using N-linked glycosylation of
PD… In addition, we consider the potential impacts of PD-L1 N-linked glycosylation on clinical …