Naturally derived indole alkaloids targeting regulated cell death (RCD) for cancer therapy: from molecular mechanisms to potential therapeutic targets

R Qin, FM You, Q Zhao, X Xie, C Peng, G Zhan… - Journal of hematology & …, 2022 - Springer
… olaparib) to exhibit therapeutic potential against various cancers … death by indole alkaloids
against different targets is expected to … the development of new strategies for cancer therapy. …

Therapeutic potential of indole alkaloids in respiratory diseases: A comprehensive review

S Mitra, SR Prova, SA Sultana, R Das, F Nainu… - Phytomedicine, 2021 - Elsevier
… This review also discusses clinical studies exploring the therapeutic efficacy of indole
alkaloids, which have confirmed the promising benefits observed in vivo and in vitro. …

[HTML][HTML] Advances in indole-containing alkaloids as potential anticancer agents by regulating autophagy

ML Luo, W Huang, HP Zhu, C Peng, Q Zhao… - Biomedicine & …, 2022 - Elsevier
indole alkaloids' effect on tumor cells and autophagy. Then, we focus on mechanisms by
which indole alkaloids can target … The study about IADB may support novel therapeutic targets

Indole alkaloids with potential anticancer activity

D Xu, Z Xu - Current topics in medicinal chemistry, 2020 - ingentaconnect.com
Indole alkaloids have the potential to exert anticancer activity … Therefore, indole alkaloids
occupy an important position in … development of indole alkaloids as potential anticancer agents, …

Indole-based small molecules as potential therapeutic agents for the treatment of fibrosis

R Qin, Q Zhao, B Han, HP Zhu, C Peng… - Frontiers in …, 2022 - frontiersin.org
… the potential of natural indole alkaloids, semi-synthetic indole alkaloids, synthetic indole
derivatives, and indole-… is to verify the therapeutic effects and activities of indole alkaloids and its …

The current scenario of naturally occurring indole alkaloids with anticancer potential

J Song, B Zhang, M Li, J Zhang - Fitoterapia, 2023 - Elsevier
indole alkaloids constitute an important source of anticancer drug leads and candidates. The
goal of this … The goal of this review is to highlight the current scenario of naturally occurring …

The therapeutic prospects of naturally occurring and synthetic indole alkaloids for depression and anxiety disorders

S Munir, A Shahid, B Aslam, UA Ashfaq… - Evidence‐Based …, 2020 - Wiley Online Library
… However, studies on the antidepressant potential of indole alkaloids from plants or … the
potential of indole alkaloids from plants and of marine origin as well as synthetic indole alkaloids

Plant-based indole alkaloids: A comprehensive overview from a pharmacological perspective

F Omar, AM Tareq, AM Alqahtani, K Dhama… - Molecules, 2021 - mdpi.com
… Although both plant and marine sources of indole alkaloids are now being extensively … only
those indole alkaloids that have been derived from plant sources. Indole alkaloids have been …

Recent progress in biological activities of indole and indole alkaloids

TP Singh, OM Singh - Mini reviews in medicinal chemistry, 2018 - ingentaconnect.com
Indole alkaloids such as tryptophan 2 are well known for their importance in … Indole3-acetic
acid 6 as heteroauxin (plant growth hormone) bring good fortune in strengthening the indole

[HTML][HTML] Alkaloids: therapeutic potential against human coronaviruses

BC Fielding, C da Silva Maia Bezerra Filho, NSM Ismail… - Molecules, 2020 - mdpi.com
… coronavirus alkaloids were identified from the scientific literature and their potential therapeutic
… In this study, in silico studies showed an affinity of the alkaloids for binding to the receptor-…