Dendritic cells and cytokines in human inflammatory and autoimmune diseases

P Blanco, AK Palucka, V Pascual… - Cytokine & growth factor …, 2008 - Elsevier
… and are susceptible to cytokine-mediated activation. Thus, interaction of resting immature …
pro-inflammatory cytokines and skewing of T cell responses. Conversely, several cytokines are …

Inflammatory signals in dendritic cell activation and the induction of adaptive immunity

O Joffre, MA Nolte, R Spörri… - Immunological reviews, 2009 - Wiley Online Library
… of naive pathogen-specific T cells. However, it has been … and that pro-inflammatory cytokines
have the same effect. … by inflammatory cytokines are unable to induce functional T-cell

Cytokine-producing dendritic cells in the pathogenesis of inflammatory skin diseases

LM Johnson-Huang, NS McNutt, JG Krueger… - Journal of clinical …, 2009 - Springer
… produce diverse cytokines and T cell polarities. Thus, these DCs may be conditioned by the
skin microenvironment to produce a specific array of inflammatory cytokines and chemokines…

Differential induction of inflammatory cytokines by dendritic cells treated with novel TLR-agonist and cytokine based cocktails: targeting dendritic cells in autoimmunity

SS Jensen, M Gad - Journal of inflammation, 2010 - Springer
… Identification of cocktails with the capability to induce secretion of the Th-1 promoting
cytokines IL-12p70 and TNFα from human dendritic cells The two pro-inflammatory cytokines IL-…

Multiple sclerosis is associated with high levels of circulating dendritic cells secreting pro-inflammatory cytokines

YM Huang, BG Xiao, V Özenci, M Kouwenhoven… - Journal of …, 1999 - Elsevier
… role for dendritic cells (DC) in the control of immunity by priming and tolerising T cells. DC …
secrete cytokines to initiate immune responses. In multiple sclerosis (MS), autoreactive T …

Pro‐inflammatory cytokines and prostaglandins induce maturation of potent immunostimulatory dendritic cells under fetal calf serum‐free conditions

H Jonuleit, U Kühn, G Müller… - European journal of …, 1997 - Wiley Online Library
… 2.2 Cytokines All cytokines used in this study were recombinant human proteins and used
at plateau concentration to induce optimal growth of dendritic cells. Final concentrations used …

Increased production of pro-inflammatory cytokines and enhanced T cell responses after activation of human dendritic cells with IL-1 and CD40 ligand

A Wesa, A Galy - BMC immunology, 2002 - Springer
… microbial, inflammatory and immune signals regulate the activation of dendritic cells (DC),
determining their ability to interact with naïve T cells and to produce cytokines that direct T cell

Reciprocal activating interaction between dendritic cells and pamidronate-stimulated γδ T cells: role of CD86 and inflammatory cytokines

L Conti, R Casetti, M Cardone, B Varano… - The Journal of …, 2005 - journals.aai.org
We investigated the interactions between human monocyte-derived dendritic cells (DCs)
and Ag-activated circulating TCR-γδ-expressing lymphocytes (Vδ2). Coculture of immature …

Differential Regulation of Inflammatory Cytokine Secretion by Human Dendritic Cells upon Chlamydia trachomatis Infection

A Gervassi, MR Alderson, R Suchland… - Infection and …, 2004 - Am Soc Microbiol
… trachomatis infections are associated with tissue inflammation and pathology. Dendritic cells
(… are a source of inflammatory cytokines. To determine the potential contribution of DC to the …

Induction of an anti-inflammatory cytokine, IL-10, in dendritic cells after toll-like receptor signaling

R Samarasinghe, P Tailor, T Tamura… - … interferon & cytokine …, 2006 - liebertpub.com
… ) is an anti-inflammatory cytokine that modulates innate and adaptive immunity. IL-10
transcripts and the protein were induced in murine bone marrow-derived dendritic cells (BMDCs) …