Systemic effect comparisons of six inhaled corticosteroid preparations

RJ Martin, SJ Szefler, VM Chinchilli, M Kraft… - American journal of …, 2002 - atsjournals.org
… Keywords: inhaled corticosteroids; … Inhaled corticosteroids (ICS) are being recommended
for treatment of all stages of persistent asthma (1). The choice of an ICS is often based on …

Inhaled corticosteroids: benefits and risks

DS Robinson, DM Geddes - Journal of Asthma, 1996 - Taylor & Francis
… lung function and symptom control with increasing dose with no clear plateau (… response.
The same group went on to show evidence of doseresponse effect up to 3.2 mg/day of inhaled

Inhaled corticosteroids in lung diseases

HH Raissy, HW Kelly, M Harkins… - American journal of …, 2013 - atsjournals.org
… are receptor mediated, corticosteroids exhibit a log–dose linear effect; thus, the clinical
dose response is often described as flat because doubling the dose is relatively ineffective in …

Direct and indirect bronchoprovocation tests in doseresponse studies of inhaled corticosteroids: Past, present, and future directions

CM Blais, BE Davis, P Nair, DW Cockcroft - Allergy, 2021 - Wiley Online Library
Inhaled corticosteroids (ICS) are a mainstay of treatment in eosinophilic asthma. Many studies
have explored the doseresponse effect … current knowledge of the doseresponse, or lack …

Deposition and effects of inhaled corticosteroids

SP Newman - Clinical pharmacokinetics, 2003 - Springer
… Our understanding of the effects and adverse effects of different inhaled corticosteroid doses
is hampered by the fact that the dose actually received by the patient may bear little relation …

Dose-response effect for adrenal suppression with repeated twice daily inhaled fluticasone propionate and triamcinolone acetonide in adult asthmatics

AM Wilson, LC McFARLANE… - American journal of …, 1997 - atsjournals.org
Inhaled corticosteroids have now gained widespread acceptance as first-line anti-… It is well
recognized that all inhaled corticosteroids are associated with dose-related systemic adverse …

Clinical dose-response relationship of fluticasone propionate in adults with asthma

M Masoli, M Weatherall, S Holt, R Beasley - Thorax, 2004 - thorax.bmj.com
… the findings of our meta-analysis both with other dose-response studies of fluticasone not
meeting our inclusion criteria and with dose-response studies of other inhaled corticosteroids. …

[HTML][HTML] How do we measure the effectiveness of inhaled corticosteroids in clinical studies?

TT Hansel - Respiratory medicine, 2004 - Elsevier
Inhaled corticosteroids (ICSs) are recommend as first line therapy for all asthmatic patients
with persistent symptoms and are the most effective therapy currently available for the …

Efficacy and safety of inhaled corticosteroids: new developments

PJ Barnes, S Pedersen, WW Busse - American journal of respiratory …, 1998 - atsjournals.org
… ; a doseresponse relationship for inhaled BUD therapy has … doseresponse studies of
inhaled corticosteroids, this study showed significant differences in response between each dose

Inhaled corticosteroids in COPD and the risk of serious pneumonia

S Suissa, V Patenaude, F Lapi, P Ernst - Thorax, 2013 - thorax.bmj.com
Inhaled corticosteroids are known to increase the risk of developing pneumonia in patients
with chronic obstructive pulmonary disease (COPD), but it is unclear whether this risk varies …