Are inhaled corticosteroids associated with an increased risk of fracture in children?

TP van Staa, N Bishop, HGM Leufkens… - Osteoporosis …, 2004 - Springer
… of fracture during exposure to inhaled corticosteroid treatment. The period of exposure was
taken as the time-period from start of inhaled corticosteroid … for group 3 (children using only …

Bone mineral density and fracture risk with long-term use of inhaled corticosteroids in patients with asthma: systematic review and meta-analysis

YK Loke, D Gilbert, M Thavarajah, P Blanco… - BMJ open, 2015 - bmjopen.bmj.com
… We identified one large long-term RCT in children that reported adjusted fracture rate of
5.7 per 100 patient years with budesonide as compared to 5.1 per 100 patient years with …

Inhaled corticosteroids and the risk of fractures in children and adolescents

RG Schlienger, SS Jick, CR Meier - Pediatrics, 2004 - publications.aap.org
… , fractures in children, glucocorticoids Current guidelines recommend the use of inhaled
corticosteroids for children and … Inhalation targets corticosteroids directly to the site of airway …

Association between inhaled corticosteroid use and bone fracture in children with asthma

N Gray, A Howard, J Zhu, LY Feldman, T To - JAMA pediatrics, 2018 - jamanetwork.com
… There is concern that, similar to systemic corticosteroids, inhaled corticosteroids may have
… risk of bone fracture associated with inhaled corticosteroid use in children with asthma. …

Inhaled corticosteroids in children: effects on bone mineral density and growth

AL Fuhlbrigge, HW Kelly - The Lancet Respiratory Medicine, 2014 - thelancet.com
… However, study findings show that children with asthma … that children who receive long-term
inhaled corticosteroid therapy for … The effects of inhaled corticosteroids on growth seem to be …

Effects of inhaled corticosteroids on bone

KJ Mortimer, TW Harrison, AE Tattersfield - Annals of Allergy, Asthma & …, 2005 - Elsevier
… in fractures in people taking an inhaled corticosteroidchildren taking an inhaled corticosteroid,
although target adult height is usually achieved. Conclusion: Since osteoporotic fracture

Asthma, bones and corticosteroids: Are inhaled corticosteroids associated with fractures in children with asthma?

SE Zieck, J George, BA Blakeley… - … paediatrics and child …, 2017 - Wiley Online Library
… asthma and prevent exacerbations is inhaled corticosteroids (ICSs). Systemic … fracture risk
in children with asthma. The aim of this study was to investigate the fracture rates in children

Safety of inhaled corticosteroids in children

DB Allen - Pediatric pulmonology, 2002 - Wiley Online Library
Inhaled corticosteroids (ICS) are now first‐line therapy for persistent asthma in children.
The major safety concerns of long‐term ICS therapy for childhood asthma are potential effects …

Inhaled corticosteroids, bone density, and risk of fracture

PN Sambrook - The Lancet, 2000 - thelancet.com
inhaled corticosteroids for a median of 6 years. The researchers found a significant inverse
relation between cumulative inhaled corticosteroid dose … use of inhaled corticosteroids, these …

Effects of inhaled corticosteroids on growth, bone metabolism, and adrenal function

PM Wolfgram, DB Allen - Advances in pediatrics, 2017 - advancesinpediatrics.com
… disease of children, and inhaled corticosteroids (ICS) are the … ICS currently approved for and
commonly used by children … FP), mometasone furoate, ciclesonide (CIC), and triamcinolone …