Inhaled corticosteroids: potency, dose equivalence and therapeutic index
PT Daley‐Yates - British journal of clinical pharmacology, 2015 - Wiley Online Library
… and therapeutic index, and concludes that higher potency can potentially improve the
therapeutic index. … the relationship between inhaled corticosteroid potency and therapeutic index …
therapeutic index. … the relationship between inhaled corticosteroid potency and therapeutic index …
Establishing a therapeutic index for the inhaled corticosteroids: part I: pharmacokinetic/pharmacodynamic comparison of the inhaled corticosteroids
HW Kelly - Journal of allergy and clinical immunology, 1998 - Elsevier
The inhaled corticosteroids contain physicochemical differences that alter both glucocorticoid
receptor-binding characteristics and the pharmacokinetic variables of these drugs. …
receptor-binding characteristics and the pharmacokinetic variables of these drugs. …
Establishing a therapeutic index for the inhaled corticosteroids: Part II: Comparisons of systemic activity and safety among different inhaled corticosteroids
CA Sorkness - Journal of allergy and clinical immunology, 1998 - Elsevier
… that low to medium doses of inhaled corticosteroids do not cause cataracts or glaucoma.
Patients requiring high-dose inhaled corticosteroids should be monitored for adverse effects, …
Patients requiring high-dose inhaled corticosteroids should be monitored for adverse effects, …
Therapeutic index of inhaled corticosteroids in asthma: A dose–response comparison on airway hyperresponsiveness and adrenal axis suppression
P Daley‐Yates, N Brealey, S Thomas… - British Journal of …, 2021 - Wiley Online Library
… This study provides evidence that ICS may differ in their therapeutic index. When compared
at therapeutic doses, fluticasone furoate, with higher anti-inflammatory activity and greater …
at therapeutic doses, fluticasone furoate, with higher anti-inflammatory activity and greater …
Comparison of inhaled corticosteroids: an update
HW Kelly - Annals of Pharmacotherapy, 2009 - journals.sagepub.com
… of the inhaled corticosteroids have sufficient therapeutic indexes to provide similar efficacy
and safety in low to medium doses. Whether or not some of the newer inhaled corticosteroids …
and safety in low to medium doses. Whether or not some of the newer inhaled corticosteroids …
Dose response and therapeutic index of inhaled corticosteroids in asthma
P Högger - Current opinion in pulmonary medicine, 2003 - journals.lww.com
… can be concluded that FP has a favorable therapeutic index compared with BDP or BUD. No
… therapeutic weight of the inhaled corticosteroids of the latest generation, MF and ciclesonide…
… therapeutic weight of the inhaled corticosteroids of the latest generation, MF and ciclesonide…
Dose–response evaluation of the therapeutic index for inhaled budesonide in patients with mild-to-moderate asthma
AM Wilson, BJ Lipworth - The American journal of medicine, 2000 - Elsevier
… PURPOSE: Inhaled corticosteroids have beneficial effects on pulmonary function and … We
evaluated the therapeutic index of inhaled corticosteroids in asthmatic patients by comparing …
evaluated the therapeutic index of inhaled corticosteroids in asthmatic patients by comparing …
Assessment of therapeutic index of inhaled steroids
E Israel - The Lancet, 2000 - thelancet.com
… Inhalation of corticosteroids enables the delivery of high concentrations of these agents to
… the therapeutic index of corticosteroids to such a degree that inhaled corticosteroids have …
… the therapeutic index of corticosteroids to such a degree that inhaled corticosteroids have …
[PDF][PDF] Comparing inhaled corticosteroids
GL Colice - Respiratory Care, 2000 - c.aarc.org
… understanding the therapeutic index of an inhaled corticosteroid. The therapeutic index
quantifies the … The concept of relative therapeutic indices is probably most easily understood by …
quantifies the … The concept of relative therapeutic indices is probably most easily understood by …
Intranasal corticosteroids: topical potency, systemic activity and therapeutic index
PT Daley-Yates, D Larenas-Linnemann… - Journal of asthma …, 2021 - Taylor & Francis
… for systemic adverse effects and an improved therapeutic index. It has been shown that …
multiple corticosteroid (CS) therapies could help reduce the total systemic burden of CS therapy. …
multiple corticosteroid (CS) therapies could help reduce the total systemic burden of CS therapy. …
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