Dual-targeting janus dendrimer based peptides for bone cancer: Synthesis and preliminary biological evaluation

B Jiang, J Zhao, Y Li, D He, J Pan… - Letters in Organic …, 2013 - ingentaconnect.com
… And the Janus dendrimer which consists of two dendrons with … In this paper, a Janustype
peptide dendrimer which consisted … binding assay and drug release study were evaluated. The …

Janus Dendrimers as Nanocarriers of Ibuprofen, Chlorambucil and their Anticancer Activity

LD Pedro-Hernández… - Pharmaceutical …, 2024 - ingentaconnect.com
… A Janus polyester dendrimer terminated by Asp oligopeptides on one side has also … its
biological activity was not determined [29]. Herein, we report the synthesis of Janus dendrimers

Janus PEG-based dendrimers for use in combination therapy: controlled multi-drug loading and sequential release

AL Acton, C Fante, B Flatley, S Burattini… - …, 2013 - ACS Publications
… Herein, we report a series of novel Janus dendrimers with … chemistries to afford four Janus
dendrimers, which contained varying … Release studies in plasma showed that the dendrimers

[HTML][HTML] Engineering of janus-like dendrimers with peptides derived from glycoproteins of Herpes simplex virus type 1: toward a versatile and novel antiviral platform

A Falanga, V Del Genio, EA Kaufman… - International journal of …, 2021 - mdpi.com
… Our hypothesis was that the Janus dendrimer was able to … that both the dendrimer and the
peptide dendrimers were ineffective … Some low activity was observed for the Janus dendrimer (…

Design and synthesis of novel amphiphilic Janus dendrimers for bone-targeted drug delivery

J Pan, M Wen, D Yin, B Jiang, D He, L Guo - Tetrahedron, 2012 - Elsevier
… of amphiphilic Janus dendrimers, which … dendrimers take advantage of a dendritic display
to carry multiple drug molecules and targeting moieties simultaneously. All of the dendrimers

High-generation amphiphilic Janus-dendrimers as stabilizing agents for drug suspensions

M Selin, S Nummelin, J Deleu, J Ropponen… - …, 2018 - ACS Publications
… of the Janus-dendrimers. The results showed that amphiphilic Janus-dendrimers adsorb
onto … Chemical structures and short notation of the Janus-dendrimers evaluated in this study. …

An emerging class of amphiphilic dendrimers for pharmaceutical and biomedical applications: Janus amphiphilic dendrimers

DR Sikwal, RS Kalhapure, T Govender - European Journal of …, 2017 - Elsevier
… , a new class of dendrimer, known as Janus dendrimers (JDs), … for homogeneous or
symmetrical dendrimers. Due to their unique … biocompatibility as well as other biological

[HTML][HTML] The Janus face of PAMAM dendrimers used to potentially cure nonenzymatic modifications of biomacromolecules in metabolic disorders—a critical review of …

M Labieniec-Watala, K Karolczak, K Siewiera… - Molecules, 2013 - mdpi.com
… of various dendrimers in biomedicine … review, which is a natural continuation of our earlier
review [4] and some original papers [5,6,7], we pass over basic information about dendrimer

[HTML][HTML] Strategies for the Preparation of Phosphorus Janus Dendrimers and Their Properties

J Cejas-Sánchez, A Kajetanowicz, K Grela… - Molecules, 2023 - mdpi.com
… Lastly, the phosphorus Janus dendrimers discussed in this review have demonstrated
applicability in various fields, particularly in materials science. Nonetheless, numerous other …

Biological assessment of triazine dendrimer: toxicological profiles, solution behavior, biodistribution, drug release and efficacy in a PEGylated, paclitaxel construct

ST Lo, S Stern, JD Clogston, J Zheng… - Molecular …, 2010 - ACS Publications
… third generation triazine dendrimer bearing approximately nine … Furthermore, the dendrimer
formulation slightly activates the … administered doses, and the dendrimer had an acute MTD …