High-generation amphiphilic Janus-dendrimers as stabilizing agents for drug suspensions
M Selin, S Nummelin, J Deleu, J Ropponen… - …, 2018 - ACS Publications
… used to stabilize drug suspensions of the poorly water-soluble drugs … JDs stabilize
pharmaceutical drug suspensions and the … notation of the Janus-dendrimers evaluated in this …
pharmaceutical drug suspensions and the … notation of the Janus-dendrimers evaluated in this …
Janus-type dendrimers: Synthesis, properties, and applications
F Najafi, M Salami-Kalajahi… - Journal of Molecular …, 2022 - Elsevier
… , drug suspensions, hydrogels, and cancer therapy. Although some studies on Janus dendrimers
… , their main goal was bioapplications of these dendrimers. In this work, we have studied …
… , their main goal was bioapplications of these dendrimers. In this work, we have studied …
Synthesis of amphiphilic Janus dendrimer and its application in improvement of hydrophobic drugs solubility in aqueous media
F Najafi, M Salami-Kalajahi… - European Polymer …, 2020 - Elsevier
… are one of the best candidates for enhancing biological active functions and dendritic scaffolds
[31] and drug suspensions [39]. Also, scientists have come up with different morphologies…
[31] and drug suspensions [39]. Also, scientists have come up with different morphologies…
Janus PEG-based dendrimers for use in combination therapy: controlled multi-drug loading and sequential release
AL Acton, C Fante, B Flatley, S Burattini… - …, 2013 - ACS Publications
… The RBC suspension (100 μL) was added to the dendrimer solutions and the plate was
incubated for 24 h at 37 C. The plate was then centrifuged for 10 min and the supernatants (150 …
incubated for 24 h at 37 C. The plate was then centrifuged for 10 min and the supernatants (150 …
[HTML][HTML] Properties and bioapplications of amphiphilic janus dendrimers: A Review
A Căta, IMC Ienașcu, MN Ştefănuț, D Roșu, OR Pop - Pharmaceutics, 2023 - mdpi.com
… soluble drug molecules. Amphiphilic Janus dendrimers can be adsorbed onto drug particles
… offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …
… offering a versatile platform for general use as stabilizing agents for drug suspensions [106]. …
Janus Dendrimers as Nanocarriers of Ibuprofen, Chlorambucil and their Anticancer Activity
LD Pedro-Hernández… - Pharmaceutical …, 2024 - ingentaconnect.com
… Aims: This study aimed to determine the anticancer activity of the Janus dendrimers
formed by two dendrons. One dendron conjugates with chlorambucil, and the other dendron …
formed by two dendrons. One dendron conjugates with chlorambucil, and the other dendron …
[HTML][HTML] Target-Specific Delivery and Bioavailability of Pharmaceuticals via Janus and Dendrimer Particles
… This article discusses various nanosized Janus and dendrimer … Janus-dendrimer hybrid
nanoparticles to address some limitations of standalone nanosized Janus and dendrimer …
nanoparticles to address some limitations of standalone nanosized Janus and dendrimer …
Zwitterionic Janus Dendrimer with distinct functional disparity for enhanced protein delivery
… Herein, we report for the first time a novel Janus dendrimer (JD) system, … Janus nanocarrier
controlled the in vivo release of insulin and … Diluted RBC suspension (200 μL) was mixed with …
controlled the in vivo release of insulin and … Diluted RBC suspension (200 μL) was mixed with …
Janus nanoparticles: materials, preparation and recent advances in drug delivery
LTC Tran, S Lesieur, V Faivre - Expert opinion on drug delivery, 2014 - Taylor & Francis
… A Janus dendrite is formed by linking two … most dendrimers. For example, when synthesized
with hydrophilic (charged or uncharged) and hydrophobic elements, Janus dendrimers can …
with hydrophilic (charged or uncharged) and hydrophobic elements, Janus dendrimers can …
[HTML][HTML] Vesicles from amphiphilic dumbbells and janus dendrimers: Bioinspired self-assembled structures for biomedical applications
S Taabache, A Bertin - Polymers, 2017 - mdpi.com
… , namely amphiphilic Janus dendrimers (forming dendrimersomes) and … We put our focus
on amphiphilic Janus dendrimers and … Solvent evaporation results in an aqueous suspension …
on amphiphilic Janus dendrimers and … Solvent evaporation results in an aqueous suspension …
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