Wnt/β-catenin signalling and podocyte dysfunction in proteinuric kidney disease
L Zhou, Y Liu - Nature Reviews Nephrology, 2015 - nature.com
… of Wnt/β-catenin signalling in mediating podocyte injury, and describes the therapeutic
potential of targeting this pathway for the treatment of proteinuric kidney disease. …
potential of targeting this pathway for the treatment of proteinuric kidney disease. …
Wnt/β-catenin in acute kidney injury and progression to chronic kidney disease
T Huffstater, WD Merryman, LS Gewin - Seminars in nephrology, 2020 - Elsevier
… Wnt and β-catenin activity have been localized to the proximal tubule after the ischemia-…
/β-catenin pathway is altered in human kidney disease. Transcriptomic data from human kidneys …
/β-catenin pathway is altered in human kidney disease. Transcriptomic data from human kidneys …
WNT–β-catenin signalling—a versatile player in kidney injury and repair
SJ Schunk, J Floege, D Fliser, T Speer - Nature Reviews Nephrology, 2021 - nature.com
… during acute kidney injury and cystic kidney diseases. Additionally, WNT–β-catenin signalling
is involved in CKD-associated vascular calcification and mineral bone disease. The WNT–…
is involved in CKD-associated vascular calcification and mineral bone disease. The WNT–…
Beta Catenin Signaling: Linking Renal Cell Carcinoma and Polycystic Kidney Disease
B Peruzzi, DP Bottaro - Cell Cycle, 2006 - Taylor & Francis
… in adult kidney has identified another oncogeni‑ cally relevant E3 ligase target: β‑catenin.
This … pathogenesis of polycystic kidney disease, where the identification of disease genes has …
This … pathogenesis of polycystic kidney disease, where the identification of disease genes has …
[HTML][HTML] Wnt/β-catenin signaling and kidney fibrosis
… The panoply of Wnt/β-catenin effects described in this review emphasizes the challenges
to understanding the biological impact of this pathway on kidney disease. At this point, …
to understanding the biological impact of this pathway on kidney disease. At this point, …
Wnt/β-catenin signaling: a novel target for therapeutic intervention of fibrotic kidney disease
I Hwang, E Seo, H Ha - Archives of pharmacal research, 2009 - Springer
… of many progressive chronic diseases including chronic kidney disease, continue to increase
… /β-catenin signaling pathway is essential to embryonic development in general and kidney …
… /β-catenin signaling pathway is essential to embryonic development in general and kidney …
[HTML][HTML] Role changes of β-catenin in kidney injury and repair
J Peng, Z Dong - Kidney international, 2012 - Elsevier
… disease conditions, including diabetic nephropathy, cystic kidney disease, and acute kidney
… Despite these observations, the pathological role played by β-catenin in kidney diseases is …
… Despite these observations, the pathological role played by β-catenin in kidney diseases is …
[HTML][HTML] WNT/β-catenin signaling in polycystic kidney disease
A Wuebken, KM Schmidt-Ott - Kidney international, 2011 - Elsevier
… of cystic kidney disease that do not display WNT/β-catenin … tubules is operative in certain
types of cystic kidney diseases, … role of β-catenin as a mediator of polycystic kidney disease is in …
types of cystic kidney diseases, … role of β-catenin as a mediator of polycystic kidney disease is in …
[HTML][HTML] Activation of Wnt/β-catenin pathway in monocytes derived from chronic kidney disease patients
HAM Al-Chaqmaqchi, A Moshfegh, E Dadfar… - PLoS …, 2013 - journals.plos.org
… kidney disease (CKD) have significantly increased morbidity and mortality resulting from
infections and cardiovascular diseases. … and the Wnt/β-catenin signaling pathway was the most …
infections and cardiovascular diseases. … and the Wnt/β-catenin signaling pathway was the most …
[HTML][HTML] Tubular β-catenin and FoxO3 interactions protect in chronic kidney disease
…, MM Taketo, M DeCaestecker, B Kasinath… - JCI insight, 2020 - ncbi.nlm.nih.gov
… dogma is that Wnt/β-catenin signaling promotes fibrosis and development of chronic kidney
disease (CKD). As the role of proximal tubular β-catenin signaling in CKD remains unclear, …
disease (CKD). As the role of proximal tubular β-catenin signaling in CKD remains unclear, …
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